Novel Therapeutic Devices in Heart Failure
Heart failure (HF) constitutes a significant clinical problem and is associated with a sizeable burden for the healthcare system. Numerous novel techniques, including device interventions, are investigated to improve clinical outcome. A review of the most notable currently studied devices targeting...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2022-07-01
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| Series: | Journal of Clinical Medicine |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2077-0383/11/15/4303 |
| _version_ | 1797441703202783232 |
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| author | Mateusz Guzik Szymon Urban Gracjan Iwanek Jan Biegus Piotr Ponikowski Robert Zymliński |
| author_facet | Mateusz Guzik Szymon Urban Gracjan Iwanek Jan Biegus Piotr Ponikowski Robert Zymliński |
| author_sort | Mateusz Guzik |
| collection | DOAJ |
| description | Heart failure (HF) constitutes a significant clinical problem and is associated with a sizeable burden for the healthcare system. Numerous novel techniques, including device interventions, are investigated to improve clinical outcome. A review of the most notable currently studied devices targeting pathophysiological processes in HF was performed. Interventions regarding autonomic nervous system imbalance, i.e., baroreflex activation therapy; vagus, splanchnic and cardiopulmonary nerves modulation; respiratory disturbances, i.e., phrenic nerve stimulation and synchronized diaphragmatic therapy; decongestion management, i.e., the Reprieve system, transcatheter renal venous decongestion system, Doraya, preCardia, WhiteSwell and Aquapass, are presented. Each segment is divided into subsections: potential pathophysiological target, existing evidence and weaknesses or unexplained issues. Novel therapeutic devices represent great potential in HF therapy management; however, further evidence is necessary to fully evaluate their utility. |
| first_indexed | 2024-03-09T12:28:55Z |
| format | Article |
| id | doaj.art-a573e9dac07b4267af133fe26d5f492c |
| institution | Directory Open Access Journal |
| issn | 2077-0383 |
| language | English |
| last_indexed | 2024-03-09T12:28:55Z |
| publishDate | 2022-07-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Journal of Clinical Medicine |
| spelling | doaj.art-a573e9dac07b4267af133fe26d5f492c2023-11-30T22:31:59ZengMDPI AGJournal of Clinical Medicine2077-03832022-07-011115430310.3390/jcm11154303Novel Therapeutic Devices in Heart FailureMateusz Guzik0Szymon Urban1Gracjan Iwanek2Jan Biegus3Piotr Ponikowski4Robert Zymliński5Institute of Heart Diseases, Wroclaw Medical University, 50-556 Wroclaw, PolandInstitute of Heart Diseases, Wroclaw Medical University, 50-556 Wroclaw, PolandInstitute of Heart Diseases, Wroclaw Medical University, 50-556 Wroclaw, PolandInstitute of Heart Diseases, Wroclaw Medical University, 50-556 Wroclaw, PolandInstitute of Heart Diseases, Wroclaw Medical University, 50-556 Wroclaw, PolandInstitute of Heart Diseases, Wroclaw Medical University, 50-556 Wroclaw, PolandHeart failure (HF) constitutes a significant clinical problem and is associated with a sizeable burden for the healthcare system. Numerous novel techniques, including device interventions, are investigated to improve clinical outcome. A review of the most notable currently studied devices targeting pathophysiological processes in HF was performed. Interventions regarding autonomic nervous system imbalance, i.e., baroreflex activation therapy; vagus, splanchnic and cardiopulmonary nerves modulation; respiratory disturbances, i.e., phrenic nerve stimulation and synchronized diaphragmatic therapy; decongestion management, i.e., the Reprieve system, transcatheter renal venous decongestion system, Doraya, preCardia, WhiteSwell and Aquapass, are presented. Each segment is divided into subsections: potential pathophysiological target, existing evidence and weaknesses or unexplained issues. Novel therapeutic devices represent great potential in HF therapy management; however, further evidence is necessary to fully evaluate their utility.https://www.mdpi.com/2077-0383/11/15/4303heart failurecardiorenal syndromeautonomic dysregulationrespiratory disturbancesnovel devices |
| spellingShingle | Mateusz Guzik Szymon Urban Gracjan Iwanek Jan Biegus Piotr Ponikowski Robert Zymliński Novel Therapeutic Devices in Heart Failure Journal of Clinical Medicine heart failure cardiorenal syndrome autonomic dysregulation respiratory disturbances novel devices |
| title | Novel Therapeutic Devices in Heart Failure |
| title_full | Novel Therapeutic Devices in Heart Failure |
| title_fullStr | Novel Therapeutic Devices in Heart Failure |
| title_full_unstemmed | Novel Therapeutic Devices in Heart Failure |
| title_short | Novel Therapeutic Devices in Heart Failure |
| title_sort | novel therapeutic devices in heart failure |
| topic | heart failure cardiorenal syndrome autonomic dysregulation respiratory disturbances novel devices |
| url | https://www.mdpi.com/2077-0383/11/15/4303 |
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