Zika in Pernambuco: rewriting the first outbreak
Abstract INTRODUCTION: A Zika virus epidemic was registered in 2015 in Northeast Brazil. In the State of Pernambuco, thousands of classical cases transpired, and in the following months, neurological disturbances in adults and microcephaly in newborns emerged as complications. After the peak of the...
| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Sociedade Brasileira de Medicina Tropical (SBMT)
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| Series: | Revista da Sociedade Brasileira de Medicina Tropical |
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| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822016000500553&lng=en&tlng=en |
| _version_ | 1829111652908269568 |
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| author | Carlos Alexandre Antunes de Brito Cecilia Coelho Moraes de Brito Augusto César Oliveira Marilia Rocha Caio Atanásio Carolina Asfora Júlio Dourado Matos Anton Saraiva Lima Maria Fátima Militão Albuquerque |
| author_facet | Carlos Alexandre Antunes de Brito Cecilia Coelho Moraes de Brito Augusto César Oliveira Marilia Rocha Caio Atanásio Carolina Asfora Júlio Dourado Matos Anton Saraiva Lima Maria Fátima Militão Albuquerque |
| author_sort | Carlos Alexandre Antunes de Brito |
| collection | DOAJ |
| description | Abstract INTRODUCTION: A Zika virus epidemic was registered in 2015 in Northeast Brazil. In the State of Pernambuco, thousands of classical cases transpired, and in the following months, neurological disturbances in adults and microcephaly in newborns emerged as complications. After the peak of the epidemic, the official system reported only four cases of Zika virus but over 100,000 cases of dengue virus. The vigilance system was unable to retrospectively estimate cases or to issue an alert to officially notified cases with possible inconsistence concerning specific arbovirosis diagnoses. METHODS: To evaluate the frequency of different arbovirosis diagnoses based on clinical-epidemiologic criteria, from January to April 2015, we conducted a hospital-based cross-sectional study retrospectively analyzing suspected cases of arbovirosis. RESULTS: Of 1 , 046 total suspected cases of arbovirus, 895 (86%) were classified as probable Zika virus cases, and 151 (14%) as probable dengue virus cases. The most frequent manifestations in probable Zika virus cases were exanthema (100%), pruritus (50.7%), fever (20.4%) and arthralgia (27.7%). CONCLUSIONS: In contrast to the official data, during the peak months of the arbovirosis epidemic of 2015, most cases were compatible with Zika virus infections. Hospital-based studies, although retrospective and based on secondary data from clinical files, might provide a better estimate of the number of cases relative to currently available data, if derived from several urgent care units of representative areas of a city or state.This would partially retrospectively correct some inconsistences regarding official notifications. |
| first_indexed | 2024-12-12T12:24:03Z |
| format | Article |
| id | doaj.art-a577568c01ab4a5289239871d30e44d7 |
| institution | Directory Open Access Journal |
| issn | 1678-9849 |
| language | English |
| last_indexed | 2024-12-12T12:24:03Z |
| publisher | Sociedade Brasileira de Medicina Tropical (SBMT) |
| record_format | Article |
| series | Revista da Sociedade Brasileira de Medicina Tropical |
| spelling | doaj.art-a577568c01ab4a5289239871d30e44d72022-12-22T00:24:36ZengSociedade Brasileira de Medicina Tropical (SBMT)Revista da Sociedade Brasileira de Medicina Tropical1678-984949555355810.1590/0037-8682-0245-2016S0037-86822016000500553Zika in Pernambuco: rewriting the first outbreakCarlos Alexandre Antunes de BritoCecilia Coelho Moraes de BritoAugusto César OliveiraMarilia RochaCaio AtanásioCarolina AsforaJúlio Dourado MatosAnton Saraiva LimaMaria Fátima Militão AlbuquerqueAbstract INTRODUCTION: A Zika virus epidemic was registered in 2015 in Northeast Brazil. In the State of Pernambuco, thousands of classical cases transpired, and in the following months, neurological disturbances in adults and microcephaly in newborns emerged as complications. After the peak of the epidemic, the official system reported only four cases of Zika virus but over 100,000 cases of dengue virus. The vigilance system was unable to retrospectively estimate cases or to issue an alert to officially notified cases with possible inconsistence concerning specific arbovirosis diagnoses. METHODS: To evaluate the frequency of different arbovirosis diagnoses based on clinical-epidemiologic criteria, from January to April 2015, we conducted a hospital-based cross-sectional study retrospectively analyzing suspected cases of arbovirosis. RESULTS: Of 1 , 046 total suspected cases of arbovirus, 895 (86%) were classified as probable Zika virus cases, and 151 (14%) as probable dengue virus cases. The most frequent manifestations in probable Zika virus cases were exanthema (100%), pruritus (50.7%), fever (20.4%) and arthralgia (27.7%). CONCLUSIONS: In contrast to the official data, during the peak months of the arbovirosis epidemic of 2015, most cases were compatible with Zika virus infections. Hospital-based studies, although retrospective and based on secondary data from clinical files, might provide a better estimate of the number of cases relative to currently available data, if derived from several urgent care units of representative areas of a city or state.This would partially retrospectively correct some inconsistences regarding official notifications.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822016000500553&lng=en&tlng=enZikaDengueOutbreakArbovirusSurveillance |
| spellingShingle | Carlos Alexandre Antunes de Brito Cecilia Coelho Moraes de Brito Augusto César Oliveira Marilia Rocha Caio Atanásio Carolina Asfora Júlio Dourado Matos Anton Saraiva Lima Maria Fátima Militão Albuquerque Zika in Pernambuco: rewriting the first outbreak Revista da Sociedade Brasileira de Medicina Tropical Zika Dengue Outbreak Arbovirus Surveillance |
| title | Zika in Pernambuco: rewriting the first outbreak |
| title_full | Zika in Pernambuco: rewriting the first outbreak |
| title_fullStr | Zika in Pernambuco: rewriting the first outbreak |
| title_full_unstemmed | Zika in Pernambuco: rewriting the first outbreak |
| title_short | Zika in Pernambuco: rewriting the first outbreak |
| title_sort | zika in pernambuco rewriting the first outbreak |
| topic | Zika Dengue Outbreak Arbovirus Surveillance |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822016000500553&lng=en&tlng=en |
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