SIV antigen immunization induces transient antigen-specific T cell responses and selectively activates viral replication in draining lymph nodes in retroviral suppressed rhesus macaques

SIV antigen immunization induces transient antigen-specific T cell responses and selectively activates viral replication in draining lymph nodes in retroviral suppressed rhesus macaques

<p>Abstract</p> <p>Background</p> <p>HIV infection causes a qualitative and quantitative loss of CD4<sup>+ </sup>T cell immunity. The institution of anti-retroviral therapy (ART) restores CD4<sup>+ </sup>T cell responses to many pathogens, but HI...

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Bibliographic Details
Main Authors: Barry Peter A, Clements Janice E, Aye Pyone P, Gama Lucio, Hu Haitao, Lackner Andrew A, Weissman Drew
Format: Article
Language:English
Published: BMC 2011-07-01
Series:Retrovirology
Online Access:http://www.retrovirology.com/content/8/1/57

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