Hypertriglyceridemia and atherosclerosis

Abstract Atherosclerotic cardiovascular disease (ASCVD) is the leading cause of death and it has been confirmed that increased low density lipoprotein cholesterol (LDL-C) is an independent risk factor for atherosclerosis. Recently, the increasing evidence has showed that hypertriglyceridemia is asso...

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Main Authors: Jia Peng, Fei Luo, Guiyun Ruan, Ran Peng, Xiangping Li
Format: Article
Language:English
Published: BMC 2017-12-01
Series:Lipids in Health and Disease
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12944-017-0625-0
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author Jia Peng
Fei Luo
Guiyun Ruan
Ran Peng
Xiangping Li
author_facet Jia Peng
Fei Luo
Guiyun Ruan
Ran Peng
Xiangping Li
author_sort Jia Peng
collection DOAJ
description Abstract Atherosclerotic cardiovascular disease (ASCVD) is the leading cause of death and it has been confirmed that increased low density lipoprotein cholesterol (LDL-C) is an independent risk factor for atherosclerosis. Recently, the increasing evidence has showed that hypertriglyceridemia is associated with incremental ASCVD risk. But the proatherogenic mechanism of triglyceride (TG) remains unclear. Therefore, this article focuses on the clinical studies and proatherogenic mechanism related to hypertriglyceridemia, in order to provide reference for the prevention and treatment of ASCVD.
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spelling doaj.art-a579abbc6b6a44d69f1c56fe2673803c2022-12-22T01:30:36ZengBMCLipids in Health and Disease1476-511X2017-12-0116111210.1186/s12944-017-0625-0Hypertriglyceridemia and atherosclerosisJia Peng0Fei Luo1Guiyun Ruan2Ran Peng3Xiangping Li4Department of Cardiovascular Medicine, The Second Xiangya Hospital, Central South UniversityDepartment of Cardiovascular Medicine, The Second Xiangya Hospital, Central South UniversityDepartment of Cardiovascular Medicine, The Second Xiangya Hospital, Central South UniversityDepartment of Cardiovascular Medicine, The Second Xiangya Hospital, Central South UniversityDepartment of Cardiovascular Medicine, The Second Xiangya Hospital, Central South UniversityAbstract Atherosclerotic cardiovascular disease (ASCVD) is the leading cause of death and it has been confirmed that increased low density lipoprotein cholesterol (LDL-C) is an independent risk factor for atherosclerosis. Recently, the increasing evidence has showed that hypertriglyceridemia is associated with incremental ASCVD risk. But the proatherogenic mechanism of triglyceride (TG) remains unclear. Therefore, this article focuses on the clinical studies and proatherogenic mechanism related to hypertriglyceridemia, in order to provide reference for the prevention and treatment of ASCVD.http://link.springer.com/article/10.1186/s12944-017-0625-0TriglycerideLipoproteinAtherosclerosisAtherosclerotic cardiovascular disease
spellingShingle Jia Peng
Fei Luo
Guiyun Ruan
Ran Peng
Xiangping Li
Hypertriglyceridemia and atherosclerosis
Lipids in Health and Disease
Triglyceride
Lipoprotein
Atherosclerosis
Atherosclerotic cardiovascular disease
title Hypertriglyceridemia and atherosclerosis
title_full Hypertriglyceridemia and atherosclerosis
title_fullStr Hypertriglyceridemia and atherosclerosis
title_full_unstemmed Hypertriglyceridemia and atherosclerosis
title_short Hypertriglyceridemia and atherosclerosis
title_sort hypertriglyceridemia and atherosclerosis
topic Triglyceride
Lipoprotein
Atherosclerosis
Atherosclerotic cardiovascular disease
url http://link.springer.com/article/10.1186/s12944-017-0625-0
work_keys_str_mv AT jiapeng hypertriglyceridemiaandatherosclerosis
AT feiluo hypertriglyceridemiaandatherosclerosis
AT guiyunruan hypertriglyceridemiaandatherosclerosis
AT ranpeng hypertriglyceridemiaandatherosclerosis
AT xiangpingli hypertriglyceridemiaandatherosclerosis