Glycogen synthase kinase 3 inhibition enhances mineral nodule formation by cementoblasts in vitro

Abstract This study aimed to investigate whether GSK-3 inhibition (CHIR99021) effectively promoted mineralization by cementoblasts (OCCM-30). OCCM-30 cells were used and treated with different concentrations of CHIR99021 (2.5, 5, and 10 mM). Experiments included proliferation and viability, cellular...

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Main Authors: Henrique ABDALLA, Rafael STORINO, Amanda BANDEIRA, Lucas TEIXEIRA, Ana MILLÁS, Paulo LISBOA-FILHO, Kamila KANTOVITZ, Francisco NOCITI JUNIOR
Format: Article
Language:English
Published: Sociedade Brasileira de Pesquisa Odontológica 2023-11-01
Series:Brazilian Oral Research
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1806-83242023000100294&tlng=en