Nanoparticles: New agents toward treatment of leishmaniasis
Leishmaniasis is a widespread disease that causes 20,000 to 30,000 deaths annually, making it a major health problem in endemic areas. Because of low-performance medications, drug delivery poses a great challenge for better treatment of leishmaniasis. The present study's purpose was to review t...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2020-08-01
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| Series: | Parasite Epidemiology and Control |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2405673120300258 |
| _version_ | 1818519832664997888 |
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| author | Amir Nafari Koroush Cheraghipour Maryam Sepahvand Ghazal Shahrokhi Esraa Gabal Hossein Mahmoudvand |
| author_facet | Amir Nafari Koroush Cheraghipour Maryam Sepahvand Ghazal Shahrokhi Esraa Gabal Hossein Mahmoudvand |
| author_sort | Amir Nafari |
| collection | DOAJ |
| description | Leishmaniasis is a widespread disease that causes 20,000 to 30,000 deaths annually, making it a major health problem in endemic areas. Because of low-performance medications, drug delivery poses a great challenge for better treatment of leishmaniasis. The present study's purpose was to review the application of nanoparticles as a new method in leishmaniasis treatment. To identify all relevant literature, we searched Web of Sciences, Scopus, PubMed, NCBI, Scielo, and Google Scholar, and profiled studies published between 1986 and 2019. In the present study, we tried to identify different research efforts in different conditions that examined the influence of various nanoparticles on different forms of leishmaniasis. In this way, we could compare their results and obtain a reliable conclusion from the most recent studies on this subject. Our review's results indicate that incorporating nanoparticles with chemical drugs improves the quality, efficiency, and sustainability of drugs and reduces their costs. Finally, considering the use of nanoparticles in the destruction of parasites, their inhibitory effect (making drugs more effective and less harmful), and their utility in making effective vaccines to prevent and fight against parasites, further research on this issue is highly recommended. |
| first_indexed | 2024-12-11T01:29:20Z |
| format | Article |
| id | doaj.art-a57da32fcc10438e90c4c603e865cb8c |
| institution | Directory Open Access Journal |
| issn | 2405-6731 |
| language | English |
| last_indexed | 2024-12-11T01:29:20Z |
| publishDate | 2020-08-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Parasite Epidemiology and Control |
| spelling | doaj.art-a57da32fcc10438e90c4c603e865cb8c2022-12-22T01:25:25ZengElsevierParasite Epidemiology and Control2405-67312020-08-0110e00156Nanoparticles: New agents toward treatment of leishmaniasisAmir Nafari0Koroush Cheraghipour1Maryam Sepahvand2Ghazal Shahrokhi3Esraa Gabal4Hossein Mahmoudvand5Student Research Committee, Lorestan University of Medical Sciences, Khorramabad, IranRazi Herbal Medicines Research Center, Lorestan University of Medical Sciences, Khorramabad, IranStudent Research Committee, Lorestan University of Medical Sciences, Khorramabad, IranStudent Research Committee, Lorestan University of Medical Sciences, Khorramabad, IranAgricultural Science and Resource Management in the Tropics and Subtropics, Bonn University, GermanyRazi Herbal Medicines Research Center, Lorestan University of Medical Sciences, Khorramabad, Iran; Corresponding author.Leishmaniasis is a widespread disease that causes 20,000 to 30,000 deaths annually, making it a major health problem in endemic areas. Because of low-performance medications, drug delivery poses a great challenge for better treatment of leishmaniasis. The present study's purpose was to review the application of nanoparticles as a new method in leishmaniasis treatment. To identify all relevant literature, we searched Web of Sciences, Scopus, PubMed, NCBI, Scielo, and Google Scholar, and profiled studies published between 1986 and 2019. In the present study, we tried to identify different research efforts in different conditions that examined the influence of various nanoparticles on different forms of leishmaniasis. In this way, we could compare their results and obtain a reliable conclusion from the most recent studies on this subject. Our review's results indicate that incorporating nanoparticles with chemical drugs improves the quality, efficiency, and sustainability of drugs and reduces their costs. Finally, considering the use of nanoparticles in the destruction of parasites, their inhibitory effect (making drugs more effective and less harmful), and their utility in making effective vaccines to prevent and fight against parasites, further research on this issue is highly recommended.http://www.sciencedirect.com/science/article/pii/S2405673120300258LeishmaniasisNano drugsTreatmentLeishmaniaParasiteNanotechnology |
| spellingShingle | Amir Nafari Koroush Cheraghipour Maryam Sepahvand Ghazal Shahrokhi Esraa Gabal Hossein Mahmoudvand Nanoparticles: New agents toward treatment of leishmaniasis Parasite Epidemiology and Control Leishmaniasis Nano drugs Treatment Leishmania Parasite Nanotechnology |
| title | Nanoparticles: New agents toward treatment of leishmaniasis |
| title_full | Nanoparticles: New agents toward treatment of leishmaniasis |
| title_fullStr | Nanoparticles: New agents toward treatment of leishmaniasis |
| title_full_unstemmed | Nanoparticles: New agents toward treatment of leishmaniasis |
| title_short | Nanoparticles: New agents toward treatment of leishmaniasis |
| title_sort | nanoparticles new agents toward treatment of leishmaniasis |
| topic | Leishmaniasis Nano drugs Treatment Leishmania Parasite Nanotechnology |
| url | http://www.sciencedirect.com/science/article/pii/S2405673120300258 |
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