Immunosuppression with Calcineurin Inhibitor after Renal Transplant Failure Inhibits Allosensitization

Immunosuppression with Calcineurin Inhibitor after Renal Transplant Failure Inhibits Allosensitization

Immunosuppression withdrawal after graft failure seems to favor sensitization. A high percentage of calculated panel-reactive antibody (cPRA) and the development of de novo donor specific antibodies (dnDSA) indicate human leukocyte antigen (HLA) sensitization and may hinder the option of retransplan...

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Bibliographic Details
Main Authors: Covadonga López del Moral Cuesta, Sandra Guiral Foz, David Gómez Pereda, José Luis Pérez Canga, Marina de Cos Gómez, Jaime Mazón Ruiz, Ana García Santiago, José Iñigo Romón Alonso, Rosalía Valero San Cecilio, Emilio Rodrigo Calabia, David San Segundo Arribas, Marcos López Hoyos, Juan Carlos Ruiz San Millán
Format: Article
Language:English
Published: MDPI AG 2020-03-01
Series:Biomedicines
Subjects:
allosensitization
donor-specific antibody
calcineurin inhibitor
graft nephrectomy
Online Access:https://www.mdpi.com/2227-9059/8/4/72

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