The Immunomodulatory Effect of IrSPI, a Tick Salivary Gland Serine Protease Inhibitor Involved in <i>Ixodes ricinus</i> Tick Feeding

The Immunomodulatory Effect of IrSPI, a Tick Salivary Gland Serine Protease Inhibitor Involved in <i>Ixodes ricinus</i> Tick Feeding

Ticks are the most important vectors of pathogens affecting both domestic and wild animals worldwide. Hard tick feeding is a slow process&#8212;taking up to several days&#8212;and necessitates extended control over the host response. The success of the feeding process depends upon injection...

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Bibliographic Details
Main Authors: Adrien A. Blisnick, Ladislav Šimo, Catherine Grillon, Fabienne Fasani, Sébastien Brûlé, Bernard Le Bonniec, Eric Prina, Maud Marsot, Anthony Relmy, Sandra Blaise-Boisseau, Jennifer Richardson, Sarah I. Bonnet
Format: Article
Language:English
Published: MDPI AG 2019-10-01
Series:Vaccines
Subjects:
<i>ixodes ricinus</i>
tick–host–pathogen interactions
anti-tick vaccine
serine protease inhibitor
immunomodulator
macrophages
lymphocytes
Online Access:https://www.mdpi.com/2076-393X/7/4/148

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