Regulation of T Cell Activities in Rheumatoid Arthritis by the Novel Fusion Protein IgD-Fc-Ig

Regulation of T Cell Activities in Rheumatoid Arthritis by the Novel Fusion Protein IgD-Fc-Ig

Rheumatoid arthritis (RA) is an autoimmune disease characterized by chronic inflammation and T cell hyper-activation. Emerging evidence has shown that the stimulation of immunoglobulin D (IgD) induces T cell activation and may contribute to disease pathogenesis. In this study, the sIgD concentration...

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Bibliographic Details
Main Authors: Jing Zhang, Xiaoxi Hu, Xiaojie Dong, Wensheng Chen, Lingling Zhang, Yan Chang, Yujing Wu, Wei Wei
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-05-01
Series:Frontiers in Immunology
Subjects:
immunoglobulin D
rheumatoid arthritis
collagen-induced arthritis
IgD-Fc-Ig fusion protein
T cells
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2020.00755/full

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