Planispine A Sensitized Cancer Cells to Cisplatin by Inhibiting the Fanconi Anemia Pathway

Planispine A Sensitized Cancer Cells to Cisplatin by Inhibiting the Fanconi Anemia Pathway

The use of cisplatin as a chemotherapeutic drug is impeded by the development of drug resistance. Combination therapies of a chemosensitizer for cisplatin have been studied, but with little success, and the search for an effective combination therapy is continuing. Our earlier reports have shown tha...

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Bibliographic Details
Main Authors: Thangjam Davis Singh, Ningthoujam Indrajit Singh, Khuraijam Mrinalini Devi, Remmei Meiguilungpou, Lhaineichong Khongsai, Lisam Shanjukumar Singh, Naresh Chandra Bal, Ningombam Swapana, Chingakham Brajakishor Singh, Thiyam Ramsing Singh
Format: Article
Language:English
Published: MDPI AG 2022-10-01
Series:Molecules
Subjects:
<i>Zanthoxylum</i>
cisplatin
apoptosis
FANCD2
chemotherapy
Online Access:https://www.mdpi.com/1420-3049/27/21/7288

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