Knock-Down of Histidyl-tRNA Synthetase Causes Cell Cycle Arrest and Apoptosis of Neuronal Progenitor Cells in vivo
Histidyl-tRNA Synthetase (HARS) is a member of the aminoacyl-tRNA synthetase family, which attach amino acids to their associated tRNA molecules. This reaction is a crucial step in protein synthesis that must be carried out in every cell of an organism. However, a number of tissue-specific, human ge...
Main Authors: | Ashley Waldron, Claire Wilcox, Christopher Francklyn, Alicia Ebert |
---|---|
Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2019-04-01
|
Series: | Frontiers in Cell and Developmental Biology |
Subjects: | |
Online Access: | https://www.frontiersin.org/article/10.3389/fcell.2019.00067/full |
Similar Items
-
Plant-Specific Domains and Fragmented Sequences Imply Non-Canonical Functions in Plant Aminoacyl-tRNA Synthetases
by: Yusuke Saga, et al.
Published: (2020-09-01) -
Aminoacyl-tRNA synthetases of the multi-tRNA synthetase complex and their role in tumorigenesis
by: Krishnendu Khan, et al.
Published: (2022-05-01) -
A noncanonical function of histidyl‐tRNA synthetase: inhibition of vascular hyperbranching during zebrafish development
by: Rui Ni, et al.
Published: (2018-05-01) -
Did Amino Acid Side Chain Reactivity Dictate the Composition and Timing of Aminoacyl-tRNA Synthetase Evolution?
by: Tamara L. Hendrickson, et al.
Published: (2021-03-01) -
Fine-Tuning of Alanyl-tRNA Synthetase Quality Control Alleviates Global Dysregulation of the Proteome
by: Paul Kelly, et al.
Published: (2020-10-01)