Investigating the Predictive Value of Thyroid Hormone Levels for Stroke Prognosis
Given the expansion of life expectancy, the aging of the population, and the anticipated rise in the number of stroke survivors in Europe with severe neurological consequences in the coming decades, stroke is becoming the most prevalent cause of functional disability. Therefore, the prognosis for a...
| Main Authors: | , , , , , , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2023-08-01
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| Series: | Neurology International |
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| Online Access: | https://www.mdpi.com/2035-8377/15/3/60 |
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| author | Aimilios Gkantzios Vaia Karapepera Dimitrios Tsiptsios Eirini Liaptsi Foteini Christidi Elena Gkartzonika Stella Karatzetzou Christos Kokkotis Mihail Kyrtsopoulos Anna Tsiakiri Paschalina Bebeletsi Sofia Chaidemenou Christos Koutsokostas Konstantinos Tsamakis Maria Baltzi Dimitrios Mpalampanos Nikolaos Aggelousis Konstantinos Vadikolias |
| author_facet | Aimilios Gkantzios Vaia Karapepera Dimitrios Tsiptsios Eirini Liaptsi Foteini Christidi Elena Gkartzonika Stella Karatzetzou Christos Kokkotis Mihail Kyrtsopoulos Anna Tsiakiri Paschalina Bebeletsi Sofia Chaidemenou Christos Koutsokostas Konstantinos Tsamakis Maria Baltzi Dimitrios Mpalampanos Nikolaos Aggelousis Konstantinos Vadikolias |
| author_sort | Aimilios Gkantzios |
| collection | DOAJ |
| description | Given the expansion of life expectancy, the aging of the population, and the anticipated rise in the number of stroke survivors in Europe with severe neurological consequences in the coming decades, stroke is becoming the most prevalent cause of functional disability. Therefore, the prognosis for a stroke must be timely and precise. Two databases (MEDLINE and Scopus) were searched to identify all relevant studies published between 1 January 2005 and 31 December 2022 that investigated the relationship between thyroid hormone levels and acute stroke severity, mortality, and post-hospital prognosis. Only full-text English-language articles were included. This review includes Thirty articles that were traced and incorporated into the present review. Emerging data regarding the potential predictive value of thyroid hormone levels suggests there may be a correlation between low T3 syndrome, subclinical hypothyroidism, and poor stroke outcome, especially in certain age groups. These findings may prove useful for rehabilitation and therapy planning in clinical practice. Serum thyroid hormone concentration measurement is a non-invasive, relatively harmless, and secure screening test that may be useful for this purpose. |
| first_indexed | 2024-03-10T22:21:32Z |
| format | Article |
| id | doaj.art-a58b9ad0e7de45a580be474c6dfa6d6e |
| institution | Directory Open Access Journal |
| issn | 2035-8377 |
| language | English |
| last_indexed | 2024-03-10T22:21:32Z |
| publishDate | 2023-08-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Neurology International |
| spelling | doaj.art-a58b9ad0e7de45a580be474c6dfa6d6e2023-11-19T12:15:50ZengMDPI AGNeurology International2035-83772023-08-0115392695310.3390/neurolint15030060Investigating the Predictive Value of Thyroid Hormone Levels for Stroke PrognosisAimilios Gkantzios0Vaia Karapepera1Dimitrios Tsiptsios2Eirini Liaptsi3Foteini Christidi4Elena Gkartzonika5Stella Karatzetzou6Christos Kokkotis7Mihail Kyrtsopoulos8Anna Tsiakiri9Paschalina Bebeletsi10Sofia Chaidemenou11Christos Koutsokostas12Konstantinos Tsamakis13Maria Baltzi14Dimitrios Mpalampanos15Nikolaos Aggelousis16Konstantinos Vadikolias17Neurology Department, Democritus University of Thrace, 68100 Alexandroupolis, GreeceNeurology Department, Democritus University of Thrace, 68100 Alexandroupolis, GreeceNeurology Department, Democritus University of Thrace, 68100 Alexandroupolis, GreeceNeurology Department, Democritus University of Thrace, 68100 Alexandroupolis, GreeceNeurology Department, Democritus University of Thrace, 68100 Alexandroupolis, GreeceSchool of Philosophy, University of Ioannina, 45110 Ioannina, GreeceNeurology Department, Democritus University of Thrace, 68100 Alexandroupolis, GreeceDepartment of Physical Education and Sport Science, Democritus University of Thrace, 69100 Komotini, GreeceNeurology Department, Democritus University of Thrace, 68100 Alexandroupolis, GreeceNeurology Department, Democritus University of Thrace, 68100 Alexandroupolis, GreeceNeurology Department, Democritus University of Thrace, 68100 Alexandroupolis, GreeceNeurology Department, Democritus University of Thrace, 68100 Alexandroupolis, GreeceNeurology Department, Democritus University of Thrace, 68100 Alexandroupolis, GreeceKing’s College London, Institute of Psychiatry, Psychology and Neuroscience, London SE5 8AF, UKDepartment of Physical Education and Sport Science, Democritus University of Thrace, 69100 Komotini, GreeceDepartment of Physical Education and Sport Science, Democritus University of Thrace, 69100 Komotini, GreeceDepartment of Physical Education and Sport Science, Democritus University of Thrace, 69100 Komotini, GreeceNeurology Department, Democritus University of Thrace, 68100 Alexandroupolis, GreeceGiven the expansion of life expectancy, the aging of the population, and the anticipated rise in the number of stroke survivors in Europe with severe neurological consequences in the coming decades, stroke is becoming the most prevalent cause of functional disability. Therefore, the prognosis for a stroke must be timely and precise. Two databases (MEDLINE and Scopus) were searched to identify all relevant studies published between 1 January 2005 and 31 December 2022 that investigated the relationship between thyroid hormone levels and acute stroke severity, mortality, and post-hospital prognosis. Only full-text English-language articles were included. This review includes Thirty articles that were traced and incorporated into the present review. Emerging data regarding the potential predictive value of thyroid hormone levels suggests there may be a correlation between low T3 syndrome, subclinical hypothyroidism, and poor stroke outcome, especially in certain age groups. These findings may prove useful for rehabilitation and therapy planning in clinical practice. Serum thyroid hormone concentration measurement is a non-invasive, relatively harmless, and secure screening test that may be useful for this purpose.https://www.mdpi.com/2035-8377/15/3/60strokeprognosisthyroid hormonesblood biomarkerslow-T3-syndromehypothyroidism |
| spellingShingle | Aimilios Gkantzios Vaia Karapepera Dimitrios Tsiptsios Eirini Liaptsi Foteini Christidi Elena Gkartzonika Stella Karatzetzou Christos Kokkotis Mihail Kyrtsopoulos Anna Tsiakiri Paschalina Bebeletsi Sofia Chaidemenou Christos Koutsokostas Konstantinos Tsamakis Maria Baltzi Dimitrios Mpalampanos Nikolaos Aggelousis Konstantinos Vadikolias Investigating the Predictive Value of Thyroid Hormone Levels for Stroke Prognosis Neurology International stroke prognosis thyroid hormones blood biomarkers low-T3-syndrome hypothyroidism |
| title | Investigating the Predictive Value of Thyroid Hormone Levels for Stroke Prognosis |
| title_full | Investigating the Predictive Value of Thyroid Hormone Levels for Stroke Prognosis |
| title_fullStr | Investigating the Predictive Value of Thyroid Hormone Levels for Stroke Prognosis |
| title_full_unstemmed | Investigating the Predictive Value of Thyroid Hormone Levels for Stroke Prognosis |
| title_short | Investigating the Predictive Value of Thyroid Hormone Levels for Stroke Prognosis |
| title_sort | investigating the predictive value of thyroid hormone levels for stroke prognosis |
| topic | stroke prognosis thyroid hormones blood biomarkers low-T3-syndrome hypothyroidism |
| url | https://www.mdpi.com/2035-8377/15/3/60 |
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