Spina bifida cystica and severe congenital bilateral talipes equinovarus in one twin of a monoamniotic pair: a case report
Abstract Background Spina bifida and congenital talipes equinovarus (CTEV) are common congenital malformations which may occur together and increase morbidity. Monozygous twins are particularly at risk of these malformations and discordance in one type of malformation is typical. The occurrence of b...
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| Format: | Article |
| Language: | English |
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BMC
2017-12-01
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| Series: | BMC Research Notes |
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| Online Access: | http://link.springer.com/article/10.1186/s13104-017-3108-5 |
| _version_ | 1818945966836809728 |
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| author | Benjamin Momo Kadia Desmond Aroke Frank-Leonel Tianyi Ndemazie Nkafu Bechem Christian Akem Dimala |
| author_facet | Benjamin Momo Kadia Desmond Aroke Frank-Leonel Tianyi Ndemazie Nkafu Bechem Christian Akem Dimala |
| author_sort | Benjamin Momo Kadia |
| collection | DOAJ |
| description | Abstract Background Spina bifida and congenital talipes equinovarus (CTEV) are common congenital malformations which may occur together and increase morbidity. Monozygous twins are particularly at risk of these malformations and discordance in one type of malformation is typical. The occurrence of both spina bifida and CTEV in one twin of a monozygotic pair is rare. Case presentation A 22 year-old Cameroonian primigravida at 36 weeks of a twin gestation was received in our district hospital at the expulsive phase of labour on a background of sub-optimal antenatal care. A caesarean section indicated for cephalo-pelvic disproportion was performed and life monoamniotic male twins were extracted. The first twin was normal. The second twin had spina bifida cystica and severe bilateral CTEV. Routine postnatal care was ensured and at day 2 of life, the affected twin was evacuated to a tertiary hospital for proper management. He was later on reported dead from complications of hydrocephalus. Conclusions Spina bifida cystica with severe bilateral CTEV in one twin of a monoamniotic pair illustrates the complexity in the interplay of causal factors of these malformations even among monozygotic twins who are assumed to share similar genetic and environmental features. The occurrence and poor outcome of the malformations was probably potentiated by poor antenatal care. With postnatal diagnoses, a better outcome was difficult to secure even with prompt referral. Early prenatal diagnoses and appropriate counseling of parents are cardinal. |
| first_indexed | 2024-12-20T08:07:31Z |
| format | Article |
| id | doaj.art-a58fb14d8f6c4a61b005676f0fee7207 |
| institution | Directory Open Access Journal |
| issn | 1756-0500 |
| language | English |
| last_indexed | 2024-12-20T08:07:31Z |
| publishDate | 2017-12-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Research Notes |
| spelling | doaj.art-a58fb14d8f6c4a61b005676f0fee72072022-12-21T19:47:22ZengBMCBMC Research Notes1756-05002017-12-011011410.1186/s13104-017-3108-5Spina bifida cystica and severe congenital bilateral talipes equinovarus in one twin of a monoamniotic pair: a case reportBenjamin Momo Kadia0Desmond Aroke1Frank-Leonel Tianyi2Ndemazie Nkafu Bechem3Christian Akem Dimala4Foumbot District HospitalHealth and Human Development (2HD) Research NetworkMayo Darle Sub-Divisional HospitalSchool of Health Sciences, University of NottinghamHealth and Human Development (2HD) Research NetworkAbstract Background Spina bifida and congenital talipes equinovarus (CTEV) are common congenital malformations which may occur together and increase morbidity. Monozygous twins are particularly at risk of these malformations and discordance in one type of malformation is typical. The occurrence of both spina bifida and CTEV in one twin of a monozygotic pair is rare. Case presentation A 22 year-old Cameroonian primigravida at 36 weeks of a twin gestation was received in our district hospital at the expulsive phase of labour on a background of sub-optimal antenatal care. A caesarean section indicated for cephalo-pelvic disproportion was performed and life monoamniotic male twins were extracted. The first twin was normal. The second twin had spina bifida cystica and severe bilateral CTEV. Routine postnatal care was ensured and at day 2 of life, the affected twin was evacuated to a tertiary hospital for proper management. He was later on reported dead from complications of hydrocephalus. Conclusions Spina bifida cystica with severe bilateral CTEV in one twin of a monoamniotic pair illustrates the complexity in the interplay of causal factors of these malformations even among monozygotic twins who are assumed to share similar genetic and environmental features. The occurrence and poor outcome of the malformations was probably potentiated by poor antenatal care. With postnatal diagnoses, a better outcome was difficult to secure even with prompt referral. Early prenatal diagnoses and appropriate counseling of parents are cardinal.http://link.springer.com/article/10.1186/s13104-017-3108-5MonoamnioticSpina bifidaTalipes equinovarusDiscordantCase report |
| spellingShingle | Benjamin Momo Kadia Desmond Aroke Frank-Leonel Tianyi Ndemazie Nkafu Bechem Christian Akem Dimala Spina bifida cystica and severe congenital bilateral talipes equinovarus in one twin of a monoamniotic pair: a case report BMC Research Notes Monoamniotic Spina bifida Talipes equinovarus Discordant Case report |
| title | Spina bifida cystica and severe congenital bilateral talipes equinovarus in one twin of a monoamniotic pair: a case report |
| title_full | Spina bifida cystica and severe congenital bilateral talipes equinovarus in one twin of a monoamniotic pair: a case report |
| title_fullStr | Spina bifida cystica and severe congenital bilateral talipes equinovarus in one twin of a monoamniotic pair: a case report |
| title_full_unstemmed | Spina bifida cystica and severe congenital bilateral talipes equinovarus in one twin of a monoamniotic pair: a case report |
| title_short | Spina bifida cystica and severe congenital bilateral talipes equinovarus in one twin of a monoamniotic pair: a case report |
| title_sort | spina bifida cystica and severe congenital bilateral talipes equinovarus in one twin of a monoamniotic pair a case report |
| topic | Monoamniotic Spina bifida Talipes equinovarus Discordant Case report |
| url | http://link.springer.com/article/10.1186/s13104-017-3108-5 |
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