Structural basis for isoform-specific kinesin-1 recognition of Y-acidic cargo adaptors
The light chains (KLCs) of the heterotetrameric microtubule motor kinesin-1, that bind to cargo adaptor proteins and regulate its activity, have a capacity to recognize short peptides via their tetratricopeptide repeat domains (KLCTPR). Here, using X-ray crystallography, we show how kinesin-1 recogn...
| Main Authors: | , , , , , , , , , |
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| 格式: | Article |
| 語言: | English |
| 出版: |
eLife Sciences Publications Ltd
2018-10-01
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| 叢編: | eLife |
| 主題: | |
| 在線閱讀: | https://elifesciences.org/articles/38362 |