An Analysis of Treatment and Prognosis of Spinal Tuberculosis: A Prospective Study done in Tertiary Care Centre
ABSTRACT Introduction: In cases of skeletal Tuberculosis (TB), spinal TB is considered to be the most hazardous. Early treatment of spinal TB brings somewhat fine projections as well. Aim: To evaluate the treatment and prognosis of patients with spinal TB. Materials and Methods: The study involve...
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
JCDR Research and Publications Private Limited
2020-06-01
|
| Series: | Journal of Clinical and Diagnostic Research |
| Subjects: | |
| Online Access: | https://jcdr.net/articles/PDF/13785/44701_CE[Ra1]_F(SHU)_PF1(AG_KM)_PFA(SL)_PB(AG_SHU)_GC(SHU)_PN(SL).pdf |
| _version_ | 1819198556257386496 |
|---|---|
| author | Shubhendu Gupta Harsh Pratap Shishodia Varun Singh |
| author_facet | Shubhendu Gupta Harsh Pratap Shishodia Varun Singh |
| author_sort | Shubhendu Gupta |
| collection | DOAJ |
| description | ABSTRACT
Introduction: In cases of skeletal Tuberculosis (TB), spinal TB is considered to be the most hazardous. Early treatment of spinal TB brings somewhat fine projections as well.
Aim: To evaluate the treatment and prognosis of patients with spinal TB.
Materials and Methods: The study involved patients with spinal TB from the period of 2017 to 2019. The total of 67 patients were included and follow-ups were made during the entire period of healing. Patients diagnosed with spinal TB and had not previously received anti-TB therapy and debridement or radical decompression surgery were included. A paired t-test was used to compare the pre-treatment and post-treatment clinical data. A p-value <0.05 was considered statistically significant.
Results: The male patients comprised of the 62.7% of the total sample size. At the final follow-up, the Visual Analogue Scale (VAS) score significantly improved from 5.99±2.11 preoperatively to 1.90±4.81 postoperatively (0<0.05), the Cobb angle significantly decreased from 16.84±6.42 preoperatively to 3.86±2.26 postoperatively (0<0.05). The Erythrocyte Sedimentation Rate (ESR) significantly decreased from 45.26±12.26 preoperatively to 9.91±6.48 postoperatively (0<0.05), and C-Reactive Protein (CRP) also significantly decreased from 49.22±42.31 to 9.84±11.53.
Conclusion: Quick treatment and diagnosis of spinal TB are essential to prevent permanent neurological disability and to minimise spinal deformity. |
| first_indexed | 2024-12-23T03:02:19Z |
| format | Article |
| id | doaj.art-a58ff15746644658bad498dc620d4ef9 |
| institution | Directory Open Access Journal |
| issn | 2249-782X 0973-709X |
| language | English |
| last_indexed | 2024-12-23T03:02:19Z |
| publishDate | 2020-06-01 |
| publisher | JCDR Research and Publications Private Limited |
| record_format | Article |
| series | Journal of Clinical and Diagnostic Research |
| spelling | doaj.art-a58ff15746644658bad498dc620d4ef92022-12-21T18:02:23ZengJCDR Research and Publications Private LimitedJournal of Clinical and Diagnostic Research2249-782X0973-709X2020-06-01146RC11RC1310.7860/JCDR/2020/44701.13785An Analysis of Treatment and Prognosis of Spinal Tuberculosis: A Prospective Study done in Tertiary Care CentreShubhendu Gupta0Harsh Pratap Shishodia1Varun Singh2Associate Professor, Department of TB and Chest, Saraswathi Institute of Medical Science, Hapur, Uttar Pradesh, India.Assistant Professor, Department of Orthopaedics, Saraswathi Institute of Medical Science, Hapur, Uttar Pradesh, India.Assistant Professor, Department of Orthopaedics, Saraswathi Institute of Medical Science, Hapur, Uttar Pradesh, India.ABSTRACT Introduction: In cases of skeletal Tuberculosis (TB), spinal TB is considered to be the most hazardous. Early treatment of spinal TB brings somewhat fine projections as well. Aim: To evaluate the treatment and prognosis of patients with spinal TB. Materials and Methods: The study involved patients with spinal TB from the period of 2017 to 2019. The total of 67 patients were included and follow-ups were made during the entire period of healing. Patients diagnosed with spinal TB and had not previously received anti-TB therapy and debridement or radical decompression surgery were included. A paired t-test was used to compare the pre-treatment and post-treatment clinical data. A p-value <0.05 was considered statistically significant. Results: The male patients comprised of the 62.7% of the total sample size. At the final follow-up, the Visual Analogue Scale (VAS) score significantly improved from 5.99±2.11 preoperatively to 1.90±4.81 postoperatively (0<0.05), the Cobb angle significantly decreased from 16.84±6.42 preoperatively to 3.86±2.26 postoperatively (0<0.05). The Erythrocyte Sedimentation Rate (ESR) significantly decreased from 45.26±12.26 preoperatively to 9.91±6.48 postoperatively (0<0.05), and C-Reactive Protein (CRP) also significantly decreased from 49.22±42.31 to 9.84±11.53. Conclusion: Quick treatment and diagnosis of spinal TB are essential to prevent permanent neurological disability and to minimise spinal deformity.https://jcdr.net/articles/PDF/13785/44701_CE[Ra1]_F(SHU)_PF1(AG_KM)_PFA(SL)_PB(AG_SHU)_GC(SHU)_PN(SL).pdfanti-tuberculosis therapypott’s diseasespinal cord |
| spellingShingle | Shubhendu Gupta Harsh Pratap Shishodia Varun Singh An Analysis of Treatment and Prognosis of Spinal Tuberculosis: A Prospective Study done in Tertiary Care Centre Journal of Clinical and Diagnostic Research anti-tuberculosis therapy pott’s disease spinal cord |
| title | An Analysis of Treatment and Prognosis of Spinal Tuberculosis: A Prospective Study done in Tertiary Care Centre |
| title_full | An Analysis of Treatment and Prognosis of Spinal Tuberculosis: A Prospective Study done in Tertiary Care Centre |
| title_fullStr | An Analysis of Treatment and Prognosis of Spinal Tuberculosis: A Prospective Study done in Tertiary Care Centre |
| title_full_unstemmed | An Analysis of Treatment and Prognosis of Spinal Tuberculosis: A Prospective Study done in Tertiary Care Centre |
| title_short | An Analysis of Treatment and Prognosis of Spinal Tuberculosis: A Prospective Study done in Tertiary Care Centre |
| title_sort | analysis of treatment and prognosis of spinal tuberculosis a prospective study done in tertiary care centre |
| topic | anti-tuberculosis therapy pott’s disease spinal cord |
| url | https://jcdr.net/articles/PDF/13785/44701_CE[Ra1]_F(SHU)_PF1(AG_KM)_PFA(SL)_PB(AG_SHU)_GC(SHU)_PN(SL).pdf |
| work_keys_str_mv | AT shubhendugupta ananalysisoftreatmentandprognosisofspinaltuberculosisaprospectivestudydoneintertiarycarecentre AT harshpratapshishodia ananalysisoftreatmentandprognosisofspinaltuberculosisaprospectivestudydoneintertiarycarecentre AT varunsingh ananalysisoftreatmentandprognosisofspinaltuberculosisaprospectivestudydoneintertiarycarecentre AT shubhendugupta analysisoftreatmentandprognosisofspinaltuberculosisaprospectivestudydoneintertiarycarecentre AT harshpratapshishodia analysisoftreatmentandprognosisofspinaltuberculosisaprospectivestudydoneintertiarycarecentre AT varunsingh analysisoftreatmentandprognosisofspinaltuberculosisaprospectivestudydoneintertiarycarecentre |