Fulminant Guillain–Barré Syndrome Post Hemorrhagic Stroke: Two Case Reports
Guillain–Barré syndrome (GBS) is an acute, immune-mediated inflammatory peripheral polyneuropathy characterized by ascending paralysis. Most GBS cases follow gastrointestinal or chest infections. Some patients have been reported either following or concomitant with head trauma, neurosurgical procedu...
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| Format: | Article |
| Language: | English |
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MDPI AG
2021-05-01
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| Series: | Neurology International |
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| Online Access: | https://www.mdpi.com/2035-8377/13/2/19 |
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| author | Sameeh Abdulmana Naif Al-Zahrani Yahya Sharahely Shahid Bashir Talal M. Al-Harbi |
| author_facet | Sameeh Abdulmana Naif Al-Zahrani Yahya Sharahely Shahid Bashir Talal M. Al-Harbi |
| author_sort | Sameeh Abdulmana |
| collection | DOAJ |
| description | Guillain–Barré syndrome (GBS) is an acute, immune-mediated inflammatory peripheral polyneuropathy characterized by ascending paralysis. Most GBS cases follow gastrointestinal or chest infections. Some patients have been reported either following or concomitant with head trauma, neurosurgical procedures, and rarely hemorrhagic stroke. The exact pathogenesis is not entirely understood. However, blood–brain barrier damage may play an essential role in triggering the autoimmune activation that leads to post-stroke GBS. Here, we present two cases of fulminant GBS following hemorrhagic stroke to remind clinicians to be aware of this rare treatable complication if a stroke patient develops unexplainable flaccid paralysis with or without respiratory distress. |
| first_indexed | 2024-03-10T11:40:38Z |
| format | Article |
| id | doaj.art-a597304a98b34aa594f829f85b3875d2 |
| institution | Directory Open Access Journal |
| issn | 2035-8377 |
| language | English |
| last_indexed | 2024-03-10T11:40:38Z |
| publishDate | 2021-05-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Neurology International |
| spelling | doaj.art-a597304a98b34aa594f829f85b3875d22023-11-21T18:29:28ZengMDPI AGNeurology International2035-83772021-05-0113219019410.3390/neurolint13020019Fulminant Guillain–Barré Syndrome Post Hemorrhagic Stroke: Two Case ReportsSameeh Abdulmana0Naif Al-Zahrani1Yahya Sharahely2Shahid Bashir3Talal M. Al-Harbi4Neuroscience Centre, Neurology Department, King Fahad Specialist Hospital-Dammam, Dammam 31444, Saudi ArabiaNeuroscience Centre, Neurology Department, King Fahad Specialist Hospital-Dammam, Dammam 31444, Saudi ArabiaNeurology Division, Medical Department, Dammam Medical Complex, Dammam 31444, Saudi ArabiaNeuroscience Centre, Neurology Department, King Fahad Specialist Hospital-Dammam, Dammam 31444, Saudi ArabiaNeuroscience Centre, Neurology Department, King Fahad Specialist Hospital-Dammam, Dammam 31444, Saudi ArabiaGuillain–Barré syndrome (GBS) is an acute, immune-mediated inflammatory peripheral polyneuropathy characterized by ascending paralysis. Most GBS cases follow gastrointestinal or chest infections. Some patients have been reported either following or concomitant with head trauma, neurosurgical procedures, and rarely hemorrhagic stroke. The exact pathogenesis is not entirely understood. However, blood–brain barrier damage may play an essential role in triggering the autoimmune activation that leads to post-stroke GBS. Here, we present two cases of fulminant GBS following hemorrhagic stroke to remind clinicians to be aware of this rare treatable complication if a stroke patient develops unexplainable flaccid paralysis with or without respiratory distress.https://www.mdpi.com/2035-8377/13/2/19Guillain–Barré syndromeGuillain–Barré following strokeintracranial hemorrhagehemorrhagic stroke complicated by radiculopathy |
| spellingShingle | Sameeh Abdulmana Naif Al-Zahrani Yahya Sharahely Shahid Bashir Talal M. Al-Harbi Fulminant Guillain–Barré Syndrome Post Hemorrhagic Stroke: Two Case Reports Neurology International Guillain–Barré syndrome Guillain–Barré following stroke intracranial hemorrhage hemorrhagic stroke complicated by radiculopathy |
| title | Fulminant Guillain–Barré Syndrome Post Hemorrhagic Stroke: Two Case Reports |
| title_full | Fulminant Guillain–Barré Syndrome Post Hemorrhagic Stroke: Two Case Reports |
| title_fullStr | Fulminant Guillain–Barré Syndrome Post Hemorrhagic Stroke: Two Case Reports |
| title_full_unstemmed | Fulminant Guillain–Barré Syndrome Post Hemorrhagic Stroke: Two Case Reports |
| title_short | Fulminant Guillain–Barré Syndrome Post Hemorrhagic Stroke: Two Case Reports |
| title_sort | fulminant guillain barre syndrome post hemorrhagic stroke two case reports |
| topic | Guillain–Barré syndrome Guillain–Barré following stroke intracranial hemorrhage hemorrhagic stroke complicated by radiculopathy |
| url | https://www.mdpi.com/2035-8377/13/2/19 |
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