Transcriptome assembly from long-read RNA-seq alignments with StringTie2

Transcriptome assembly from long-read RNA-seq alignments with StringTie2

Abstract RNA sequencing using the latest single-molecule sequencing instruments produces reads that are thousands of nucleotides long. The ability to assemble these long reads can greatly improve the sensitivity of long-read analyses. Here we present StringTie2, a reference-guided transcriptome asse...

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Bibliographic Details
Main Authors: Sam Kovaka, Aleksey V. Zimin, Geo M. Pertea, Roham Razaghi, Steven L. Salzberg, Mihaela Pertea
Format: Article
Language:English
Published: BMC 2019-12-01
Series:Genome Biology
Subjects:
Transcriptome assembly
RNA-seq
Long-read sequencing
Gene expression
Online Access:https://doi.org/10.1186/s13059-019-1910-1

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