HPRep: Quantifying Reproducibility in HiChIP and PLAC-Seq Datasets

HPRep: Quantifying Reproducibility in HiChIP and PLAC-Seq Datasets

HiChIP and PLAC-Seq are emerging technologies for studying genome-wide long-range chromatin interactions mediated by the protein of interest, enabling more sensitive and cost-efficient interrogation of protein-centric chromatin conformation. However, due to the unbalanced read distribution introduce...

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Bibliographic Details
Main Authors: Jonathan D. Rosen, Yuchen Yang, Armen Abnousi, Jiawen Chen, Michael Song, Ian R. Jones, Yin Shen, Ming Hu, Yun Li
Format: Article
Language:English
Published: MDPI AG 2021-09-01
Series:Current Issues in Molecular Biology
Subjects:
reproducibility
HiChIP
PLAC-Seq
chromatin spatial organization
Online Access:https://www.mdpi.com/1467-3045/43/2/82

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