Neurological and Psychiatric Manifestations of Long COVID-19 and Their [<sup>18</sup>F]FDG PET Findings: A Review
For more than two years, lingering sequalae of COVID-19 have been extensively investigated. Approximately 10% of individuals infected by COVID-19 have been found to experience long-term symptoms termed “long COVID-19”. The neurological and psychiatric manifestations of long COVID-19 are of particula...
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| Format: | Article |
| Language: | English |
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MDPI AG
2023-07-01
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| Series: | Diagnostics |
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| Online Access: | https://www.mdpi.com/2075-4418/13/14/2353 |
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| author | Rizwanullah Hameed Anuradha Rosario Bahadur Shashi Bhushan Singh Juwairah Sher Maia Todua Leah (Mahsa) Moradi Sanjiv Bastakoti Maeen Arslan Hanfa Ajmal Gha Young Lee Cyrus Ayubcha Thomas J. Werner Abass Alavi Mona-Elisabeth Revheim |
| author_facet | Rizwanullah Hameed Anuradha Rosario Bahadur Shashi Bhushan Singh Juwairah Sher Maia Todua Leah (Mahsa) Moradi Sanjiv Bastakoti Maeen Arslan Hanfa Ajmal Gha Young Lee Cyrus Ayubcha Thomas J. Werner Abass Alavi Mona-Elisabeth Revheim |
| author_sort | Rizwanullah Hameed |
| collection | DOAJ |
| description | For more than two years, lingering sequalae of COVID-19 have been extensively investigated. Approximately 10% of individuals infected by COVID-19 have been found to experience long-term symptoms termed “long COVID-19”. The neurological and psychiatric manifestations of long COVID-19 are of particular concern. While pathogenesis remains unclear, emerging imaging studies have begun to better elucidate certain pathological manifestation. Of specific interest is imaging with [<sup>18</sup>F]FDG PET which directly reflects cellular glycolysis often linked to metabolic and inflammatory processes. Seeking to understand the molecular basis of neurological features of long COVID-19, this review encompasses the most recent [<sup>18</sup>F]FDG PET literature in this area. |
| first_indexed | 2024-03-11T01:09:56Z |
| format | Article |
| id | doaj.art-a59f1b2efd4f4d6baf2db142d9e57828 |
| institution | Directory Open Access Journal |
| issn | 2075-4418 |
| language | English |
| last_indexed | 2024-03-11T01:09:56Z |
| publishDate | 2023-07-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Diagnostics |
| spelling | doaj.art-a59f1b2efd4f4d6baf2db142d9e578282023-11-18T18:57:34ZengMDPI AGDiagnostics2075-44182023-07-011314235310.3390/diagnostics13142353Neurological and Psychiatric Manifestations of Long COVID-19 and Their [<sup>18</sup>F]FDG PET Findings: A ReviewRizwanullah Hameed0Anuradha Rosario Bahadur1Shashi Bhushan Singh2Juwairah Sher3Maia Todua4Leah (Mahsa) Moradi5Sanjiv Bastakoti6Maeen Arslan7Hanfa Ajmal8Gha Young Lee9Cyrus Ayubcha10Thomas J. Werner11Abass Alavi12Mona-Elisabeth Revheim13Kingsbrook Jewish Medical Center, 585 Schenectady Avenue, New York, NY 11203, USAKingston Public Hospital, North Street, Kingston 4, JamaicaDepartment of Radiology, Stanford University School of Medicine, Stanford, CA 94304, USAMedical University of the Americas, 27 Jackson Road, Suite 302, Devens, MA 0134, USADepartment of Endocrinology, Tbilisi State Medical University, Vazha-Pshavela Ave. 33, 0186 Tbilisi, GeorgiaTouro University, Touro College of Pharmacy, 3 Times Square, New York, NY 10036, USARussell Hall Hospital, Dudley DY1 2HQ, UKDartmouth College Hanover, Hanover, NH 03755, USACollege of Public Health, University of South Florida, 4202 E Fowler Ave., Tampa, FL 33620, USAHarvard Medical School, 25 Shattuck St., Boston, MA 02115, USAHarvard Medical School, 25 Shattuck St., Boston, MA 02115, USADepartment of Radiology, Hospital of the University of Pennsylvania, 3400 Spruce St., Philadelphia, PA 19104, USADepartment of Radiology, Hospital of the University of Pennsylvania, 3400 Spruce St., Philadelphia, PA 19104, USAThe Intervention Center, Rikshospitalet, Division for Technology and Innovation, Oslo University Hospital, 0424 Oslo, NorwayFor more than two years, lingering sequalae of COVID-19 have been extensively investigated. Approximately 10% of individuals infected by COVID-19 have been found to experience long-term symptoms termed “long COVID-19”. The neurological and psychiatric manifestations of long COVID-19 are of particular concern. While pathogenesis remains unclear, emerging imaging studies have begun to better elucidate certain pathological manifestation. Of specific interest is imaging with [<sup>18</sup>F]FDG PET which directly reflects cellular glycolysis often linked to metabolic and inflammatory processes. Seeking to understand the molecular basis of neurological features of long COVID-19, this review encompasses the most recent [<sup>18</sup>F]FDG PET literature in this area.https://www.mdpi.com/2075-4418/13/14/2353COVID-19long COVID-19neurologicpsychiatric[<sup>18</sup>F]FDGpositron emission tomography |
| spellingShingle | Rizwanullah Hameed Anuradha Rosario Bahadur Shashi Bhushan Singh Juwairah Sher Maia Todua Leah (Mahsa) Moradi Sanjiv Bastakoti Maeen Arslan Hanfa Ajmal Gha Young Lee Cyrus Ayubcha Thomas J. Werner Abass Alavi Mona-Elisabeth Revheim Neurological and Psychiatric Manifestations of Long COVID-19 and Their [<sup>18</sup>F]FDG PET Findings: A Review Diagnostics COVID-19 long COVID-19 neurologic psychiatric [<sup>18</sup>F]FDG positron emission tomography |
| title | Neurological and Psychiatric Manifestations of Long COVID-19 and Their [<sup>18</sup>F]FDG PET Findings: A Review |
| title_full | Neurological and Psychiatric Manifestations of Long COVID-19 and Their [<sup>18</sup>F]FDG PET Findings: A Review |
| title_fullStr | Neurological and Psychiatric Manifestations of Long COVID-19 and Their [<sup>18</sup>F]FDG PET Findings: A Review |
| title_full_unstemmed | Neurological and Psychiatric Manifestations of Long COVID-19 and Their [<sup>18</sup>F]FDG PET Findings: A Review |
| title_short | Neurological and Psychiatric Manifestations of Long COVID-19 and Their [<sup>18</sup>F]FDG PET Findings: A Review |
| title_sort | neurological and psychiatric manifestations of long covid 19 and their sup 18 sup f fdg pet findings a review |
| topic | COVID-19 long COVID-19 neurologic psychiatric [<sup>18</sup>F]FDG positron emission tomography |
| url | https://www.mdpi.com/2075-4418/13/14/2353 |
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