Soluble CD40 Levels in Plasma Are Associated with Cardiovascular Disease and in Carotid Plaques with a Vulnerable Phenotype

Soluble CD40 Levels in Plasma Are Associated with Cardiovascular Disease and in Carotid Plaques with a Vulnerable Phenotype

Background and Purpose CD40 and CD40 ligand (CD40L) are costimulatory molecules of the tumor necrosis factor receptor superfamily and well known for their involvement in inflammatory diseases: atherosclerotic mouse models with disrupted CD40 signalling develop lesions of reduced size with a more sta...

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Bibliographic Details
Main Authors: Annelie Shami, Andreas Edsfeldt, Eva Bengtsson, Jan Nilsson, Angela C. Shore, Andrea Natali, Faisel Khan, Esther Lutgens, Isabel Gonçalves
Format: Article
Language:English
Published: Korean Stroke Society 2021-09-01
Series:Journal of Stroke
Subjects:
cd40
cd40 ligand
atherosclerosis
carotid arteries
inflammation
Online Access:http://www.j-stroke.org/upload/pdf/jos-2021-00178.pdf

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