Regulating inflammation through the anti-inflammatory enzyme platelet-activating factor-acetylhydrolase

Regulating inflammation through the anti-inflammatory enzyme platelet-activating factor-acetylhydrolase

Platelet-activating factor (PAF) is one of the most potent lipid mediators involved in inflammatory events. The acetyl group at the sn-2 position of its glycerol backbone is essential for its biological activity. Deacetylation induces the formation of the inactive metabolite lyso-PAF. This deacetyla...

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Detalhes bibliográficos
Principais autores:	Hugo C Castro Faria Neto, Diana M Stafforini, Stephen M Prescott, Guy A Zimmerman
Formato:	Artigo
Idioma:	English
Publicado em:	Fundação Oswaldo Cruz (FIOCRUZ) 2005-03-01
coleção:	Memorias do Instituto Oswaldo Cruz
Assuntos:	platelet-activating factor acethylhydrolase inflammatory disease sepsis
Acesso em linha:	http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762005000900014

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