p32 heterozygosity protects against age- and diet-induced obesity by increasing energy expenditure
Abstract Obesity is increasing in prevalence and has become a global public health problem. The main cause of obesity is a perturbation in energy homeostasis, whereby energy intake exceeds energy expenditure. Although mitochondrial dysfunction has been linked to the deregulation of energy homeostasi...
Main Authors: | Yong Liu, Patrick L. Leslie, Aiwen Jin, Koji Itahana, Lee M. Graves, Yanping Zhang |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2017-07-01
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Series: | Scientific Reports |
Online Access: | https://doi.org/10.1038/s41598-017-06209-9 |
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