THE METHICILLIN-RESISTANCE MEASURE OF STAPHYLOCOCCI CLINICAL STRAINS

Staphylococci playa great role in the emergence of various human illnesses. The most actual are infections caused by methicillin-resistant staphylococci. The study of methicillin susceptibility as a polyresistance marker includes the definition of the minimum inhibitory concentration (MIC) of antibi...

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Main Authors: G.M.Shub, N.G. Khodakova, I.G.Shvidenko
Format: Article
Language:Russian
Published: Saratov State Medical University 2008-06-01
Series:Саратовский научно-медицинский журнал
Subjects:
Online Access:http://www.ssmj.ru/system/files/2008_02_056_060.pdf
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author G.M.Shub
N.G. Khodakova
I.G.Shvidenko
author_facet G.M.Shub
N.G. Khodakova
I.G.Shvidenko
author_sort G.M.Shub
collection DOAJ
description Staphylococci playa great role in the emergence of various human illnesses. The most actual are infections caused by methicillin-resistant staphylococci. The study of methicillin susceptibility as a polyresistance marker includes the definition of the minimum inhibitory concentration (MIC) of antibiotic which in vitro fully suppresses the visible growth of microorganisms in the standard experiment conditions and is expressed in absolute figures (mg/l or mkg/ml). The aim of the research is the measure of MIC methicillin (oxacillin) for the clinical strains of staphylococci isolated from different clinical specimens and comparative analysis antibiotic’s MIC for Staphylococcus aureus and coagulase-negative staphylococci (CNS). The resultofthe research is the determination of the oxacillin concentration preventing growth of the methicillin-resistant clinical strains ofS.aureus and CNSwhich were detected from different profile hospitals of Saratov- general hospital №2, maternity hospital №6, children’s regional hospital and centre ofcombustiology. The methicillin-resistant of the staphylococci clinical strains in the Saratov region has not been investigated before.
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spelling doaj.art-a5af3678f0a2456aaf9d30bb85f069f02022-12-21T19:23:01ZrusSaratov State Medical UniversityСаратовский научно-медицинский журнал1995-00392076-25182008-06-01425660THE METHICILLIN-RESISTANCE MEASURE OF STAPHYLOCOCCI CLINICAL STRAINSG.M.ShubN.G. KhodakovaI.G.ShvidenkoStaphylococci playa great role in the emergence of various human illnesses. The most actual are infections caused by methicillin-resistant staphylococci. The study of methicillin susceptibility as a polyresistance marker includes the definition of the minimum inhibitory concentration (MIC) of antibiotic which in vitro fully suppresses the visible growth of microorganisms in the standard experiment conditions and is expressed in absolute figures (mg/l or mkg/ml). The aim of the research is the measure of MIC methicillin (oxacillin) for the clinical strains of staphylococci isolated from different clinical specimens and comparative analysis antibiotic’s MIC for Staphylococcus aureus and coagulase-negative staphylococci (CNS). The resultofthe research is the determination of the oxacillin concentration preventing growth of the methicillin-resistant clinical strains ofS.aureus and CNSwhich were detected from different profile hospitals of Saratov- general hospital №2, maternity hospital №6, children’s regional hospital and centre ofcombustiology. The methicillin-resistant of the staphylococci clinical strains in the Saratov region has not been investigated before.http://www.ssmj.ru/system/files/2008_02_056_060.pdfmethicillinoxacillinpolyresistancestaphylococcistrains
spellingShingle G.M.Shub
N.G. Khodakova
I.G.Shvidenko
THE METHICILLIN-RESISTANCE MEASURE OF STAPHYLOCOCCI CLINICAL STRAINS
Саратовский научно-медицинский журнал
methicillin
oxacillin
polyresistance
staphylococci
strains
title THE METHICILLIN-RESISTANCE MEASURE OF STAPHYLOCOCCI CLINICAL STRAINS
title_full THE METHICILLIN-RESISTANCE MEASURE OF STAPHYLOCOCCI CLINICAL STRAINS
title_fullStr THE METHICILLIN-RESISTANCE MEASURE OF STAPHYLOCOCCI CLINICAL STRAINS
title_full_unstemmed THE METHICILLIN-RESISTANCE MEASURE OF STAPHYLOCOCCI CLINICAL STRAINS
title_short THE METHICILLIN-RESISTANCE MEASURE OF STAPHYLOCOCCI CLINICAL STRAINS
title_sort methicillin resistance measure of staphylococci clinical strains
topic methicillin
oxacillin
polyresistance
staphylococci
strains
url http://www.ssmj.ru/system/files/2008_02_056_060.pdf
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AT ngkhodakova themethicillinresistancemeasureofstaphylococciclinicalstrains
AT igshvidenko themethicillinresistancemeasureofstaphylococciclinicalstrains
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AT ngkhodakova methicillinresistancemeasureofstaphylococciclinicalstrains
AT igshvidenko methicillinresistancemeasureofstaphylococciclinicalstrains