Orthostatic variation of pulmonary artery pressure in ambulatory heart failure patients
Abstract Aim To study effect of change in position (supine and standing) on pulmonary artery pressure (PAP) in ambulatory heart failure (HF) patients. Methods Seventeen patients with CardioMEMS® sensor and stable heart failure were consented and included in this single center study. Supine and stand...
| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Language: | English |
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BMC
2023-10-01
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| Series: | BMC Cardiovascular Disorders |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s12872-023-03534-y |
| _version_ | 1797453960939831296 |
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| author | Prince Sethi Prakash Acharya Payton Lancaster Brianna Stack Kartik Munshi Sagar Ranka Zubair Shah Andrew J. Sauer Kamal Gupta |
| author_facet | Prince Sethi Prakash Acharya Payton Lancaster Brianna Stack Kartik Munshi Sagar Ranka Zubair Shah Andrew J. Sauer Kamal Gupta |
| author_sort | Prince Sethi |
| collection | DOAJ |
| description | Abstract Aim To study effect of change in position (supine and standing) on pulmonary artery pressure (PAP) in ambulatory heart failure (HF) patients. Methods Seventeen patients with CardioMEMS® sensor and stable heart failure were consented and included in this single center study. Supine and standing measurements were obtained with at least 5 min interval between the two positions. These measurements included PAP readings utilizing the manufacturer handheld interrogator obtaining 10 s data in addition to the systemic blood pressure and heart rate recordings. Results Mean supine and standing readings and their difference (Δ) were as follows respectively: Systolic PAP were 33.4 (± 11.19), 23.6 (± 10) and Δ was 9.9 mmHg (p = 0.0001), diastolic PAP were 14.2 (± 5.6), 7.9 (± 5.7) and Δ was 6.3 mmHg (p = 0.0001) and mean PAP were 21.8 (± 7.8), 14 (± 7.2) and Δ was 7.4 mmHg (p = 0.0001) while the systemic blood pressure did not vary significantly. Conclusion There is orthostatic variation of PAP in ambulatory HF patients demonstrating a mean decline with standing in diastolic PAP by 6.3 mmHg, systolic PAP by 9.9 mmHg and mean PAP by 7.4 mmHg in absence of significant orthostatic variation in systemic blood pressure or heart rate. These findings have significant clinical implications and inform that PAP in each patient should always be measured in the same position. Since initial readings at the time of implant were taken in supine position, it may be best to use supine position or to obtain a baseline standing PAP reading if standing PAP is planned on being used. |
| first_indexed | 2024-03-09T15:30:26Z |
| format | Article |
| id | doaj.art-a5afd9cc39dc496a88cd5c131cecac08 |
| institution | Directory Open Access Journal |
| issn | 1471-2261 |
| language | English |
| last_indexed | 2024-03-09T15:30:26Z |
| publishDate | 2023-10-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Cardiovascular Disorders |
| spelling | doaj.art-a5afd9cc39dc496a88cd5c131cecac082023-11-26T12:16:59ZengBMCBMC Cardiovascular Disorders1471-22612023-10-012311510.1186/s12872-023-03534-yOrthostatic variation of pulmonary artery pressure in ambulatory heart failure patientsPrince Sethi0Prakash Acharya1Payton Lancaster2Brianna Stack3Kartik Munshi4Sagar Ranka5Zubair Shah6Andrew J. Sauer7Kamal Gupta8Department of Cardiovascular Disease, University of Kansas Medical CenterDepartment of Cardiovascular Disease, University of Kansas Medical CenterDepartment of Cardiovascular Disease, University of Kansas Medical CenterDepartment of Cardiovascular Disease, University of Kansas Medical CenterDepartment of Cardiovascular Disease, University of Kansas Medical CenterDepartment of Cardiovascular Disease, University of Kansas Medical CenterDepartment of Cardiovascular Disease, University of Kansas Medical CenterDepartment of Cardiovascular Disease, University of Kansas Medical CenterDepartment of Cardiovascular Disease, University of Kansas Medical CenterAbstract Aim To study effect of change in position (supine and standing) on pulmonary artery pressure (PAP) in ambulatory heart failure (HF) patients. Methods Seventeen patients with CardioMEMS® sensor and stable heart failure were consented and included in this single center study. Supine and standing measurements were obtained with at least 5 min interval between the two positions. These measurements included PAP readings utilizing the manufacturer handheld interrogator obtaining 10 s data in addition to the systemic blood pressure and heart rate recordings. Results Mean supine and standing readings and their difference (Δ) were as follows respectively: Systolic PAP were 33.4 (± 11.19), 23.6 (± 10) and Δ was 9.9 mmHg (p = 0.0001), diastolic PAP were 14.2 (± 5.6), 7.9 (± 5.7) and Δ was 6.3 mmHg (p = 0.0001) and mean PAP were 21.8 (± 7.8), 14 (± 7.2) and Δ was 7.4 mmHg (p = 0.0001) while the systemic blood pressure did not vary significantly. Conclusion There is orthostatic variation of PAP in ambulatory HF patients demonstrating a mean decline with standing in diastolic PAP by 6.3 mmHg, systolic PAP by 9.9 mmHg and mean PAP by 7.4 mmHg in absence of significant orthostatic variation in systemic blood pressure or heart rate. These findings have significant clinical implications and inform that PAP in each patient should always be measured in the same position. Since initial readings at the time of implant were taken in supine position, it may be best to use supine position or to obtain a baseline standing PAP reading if standing PAP is planned on being used.https://doi.org/10.1186/s12872-023-03534-yOrthostatic variationPulmonary artery pressureCardioMEMSHeart failure |
| spellingShingle | Prince Sethi Prakash Acharya Payton Lancaster Brianna Stack Kartik Munshi Sagar Ranka Zubair Shah Andrew J. Sauer Kamal Gupta Orthostatic variation of pulmonary artery pressure in ambulatory heart failure patients BMC Cardiovascular Disorders Orthostatic variation Pulmonary artery pressure CardioMEMS Heart failure |
| title | Orthostatic variation of pulmonary artery pressure in ambulatory heart failure patients |
| title_full | Orthostatic variation of pulmonary artery pressure in ambulatory heart failure patients |
| title_fullStr | Orthostatic variation of pulmonary artery pressure in ambulatory heart failure patients |
| title_full_unstemmed | Orthostatic variation of pulmonary artery pressure in ambulatory heart failure patients |
| title_short | Orthostatic variation of pulmonary artery pressure in ambulatory heart failure patients |
| title_sort | orthostatic variation of pulmonary artery pressure in ambulatory heart failure patients |
| topic | Orthostatic variation Pulmonary artery pressure CardioMEMS Heart failure |
| url | https://doi.org/10.1186/s12872-023-03534-y |
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