In-Line and Off-Line Monitoring of Skin Penetration Profiles Using Confocal Raman Spectroscopy

In-Line and Off-Line Monitoring of Skin Penetration Profiles Using Confocal Raman Spectroscopy

Ex-vivo and in-vivo skin analysis has been extensively evaluated by confocal Raman spectroscopy (CRS). The off-line measurement with a CRS-suited skin-mounted device after Franz-cell incubations is the most popular choice. However, real-time monitoring of in-line measurement has clear advantages for...

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Bibliographic Details
Main Authors: Richard Krombholz, Yali Liu, Dominique Jasmin Lunter
Format: Article
Language:English
Published: MDPI AG 2021-01-01
Series:Pharmaceutics
Subjects:
in-line and off-line measurements
confocal Raman spectroscopy
procaine-HCl penetration
PEG-23 lauryl ether
penetration enhancement
skin
Online Access:https://www.mdpi.com/1999-4923/13/1/67

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