Untargeted Metabolomics and Steroid Signatures in Urine of Male Pattern Baldness Patients after Finasteride Treatment for a Year

Untargeted Metabolomics and Steroid Signatures in Urine of Male Pattern Baldness Patients after Finasteride Treatment for a Year

Male pattern baldness (MPB) has been associated with dihydrotestosterone (DHT) expression. Finasteride treats MPB by inhibiting 5-alpha reductase and blocking DHT production. In this study, we aimed to identify metabolic differences in urinary metabolomics profiles between MPB patients after a one-y...

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Bibliographic Details
Main Authors: Yu Ra Lee, Eunju Im, Haksoon Kim, Bark Lynn Lew, Woo-Young Sim, Jeongae Lee, Han Bin Oh, Ki Jung Paeng, Jongki Hong, Bong Chul Chung
Format: Article
Language:English
Published: MDPI AG 2020-03-01
Series:Metabolites
Subjects:
male pattern baldness
liquid chromatography-tandem mass spectrometry
androgens
estrogen
finasteride
Online Access:https://www.mdpi.com/2218-1989/10/4/131

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