Acute cerebellar ataxia: A rare association of hepatitis a infection

Acute cerebellar ataxia (ACA) is a self-limited syndrome that is frequently post-infectious, most commonly following Varicella infection having an autoimmune mechanism. ACA is the commonest cause of childhood ataxia. We report a 14-year-old male who presented with acute onset wide-based gait and slu...

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Main Authors: Shweta Sharma, Prithivi R Prakash, Ananthu Narayan, Ajay Garg, Naveet Wig
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2023-01-01
Series:Annals of Indian Academy of Neurology
Subjects:
Online Access:http://www.annalsofian.org/article.asp?issn=0972-2327;year=2023;volume=26;issue=3;spage=278;epage=280;aulast=Sharma
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author Shweta Sharma
Prithivi R Prakash
Ananthu Narayan
Ajay Garg
Naveet Wig
author_facet Shweta Sharma
Prithivi R Prakash
Ananthu Narayan
Ajay Garg
Naveet Wig
author_sort Shweta Sharma
collection DOAJ
description Acute cerebellar ataxia (ACA) is a self-limited syndrome that is frequently post-infectious, most commonly following Varicella infection having an autoimmune mechanism. ACA is the commonest cause of childhood ataxia. We report a 14-year-old male who presented with acute onset wide-based gait and slurring of speech with dysdiadochokinesia, incoordination of voluntary movements, pendular knee jerk, and intentional tremors. He had worsening transaminitis and rising bilirubin during his hospital course and was subsequently found to be hepatitis A virus (HAV) immunoglobulin-M antibody positive. Thus, we report a case of ACA with HAV infection who developed jaundice after three weeks of onset of ataxia, a rarity that has not been reported so far in medical literature.
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spelling doaj.art-a5bc379741da4ce38da842cceecb28a22023-07-21T14:20:16ZengWolters Kluwer Medknow PublicationsAnnals of Indian Academy of Neurology0972-23271998-35492023-01-0126327828010.4103/aian.aian_61_23Acute cerebellar ataxia: A rare association of hepatitis a infectionShweta SharmaPrithivi R PrakashAnanthu NarayanAjay GargNaveet WigAcute cerebellar ataxia (ACA) is a self-limited syndrome that is frequently post-infectious, most commonly following Varicella infection having an autoimmune mechanism. ACA is the commonest cause of childhood ataxia. We report a 14-year-old male who presented with acute onset wide-based gait and slurring of speech with dysdiadochokinesia, incoordination of voluntary movements, pendular knee jerk, and intentional tremors. He had worsening transaminitis and rising bilirubin during his hospital course and was subsequently found to be hepatitis A virus (HAV) immunoglobulin-M antibody positive. Thus, we report a case of ACA with HAV infection who developed jaundice after three weeks of onset of ataxia, a rarity that has not been reported so far in medical literature.http://www.annalsofian.org/article.asp?issn=0972-2327;year=2023;volume=26;issue=3;spage=278;epage=280;aulast=Sharmaacute cerebellar ataxiahepatitis a virusjaundice
spellingShingle Shweta Sharma
Prithivi R Prakash
Ananthu Narayan
Ajay Garg
Naveet Wig
Acute cerebellar ataxia: A rare association of hepatitis a infection
Annals of Indian Academy of Neurology
acute cerebellar ataxia
hepatitis a virus
jaundice
title Acute cerebellar ataxia: A rare association of hepatitis a infection
title_full Acute cerebellar ataxia: A rare association of hepatitis a infection
title_fullStr Acute cerebellar ataxia: A rare association of hepatitis a infection
title_full_unstemmed Acute cerebellar ataxia: A rare association of hepatitis a infection
title_short Acute cerebellar ataxia: A rare association of hepatitis a infection
title_sort acute cerebellar ataxia a rare association of hepatitis a infection
topic acute cerebellar ataxia
hepatitis a virus
jaundice
url http://www.annalsofian.org/article.asp?issn=0972-2327;year=2023;volume=26;issue=3;spage=278;epage=280;aulast=Sharma
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AT ananthunarayan acutecerebellarataxiaarareassociationofhepatitisainfection
AT ajaygarg acutecerebellarataxiaarareassociationofhepatitisainfection
AT naveetwig acutecerebellarataxiaarareassociationofhepatitisainfection