2543 High concentrations of CXCL12 decrease pancreatic adenocarcinoma growth
OBJECTIVES/SPECIFIC AIMS: We hypothesized that CXCL12, as a biased dimer variant or secreted at dimer-dominant concentrations, would influence PDAC growth and progression. METHODS/STUDY POPULATION: PDAC cells were genetically manipulated to express dimer-promoting levels of CXCL12. These cells were...
Main Authors: | Emily Vonderhaar, Michael Dwinell, Ishan R. Roy, Donna M. McAllister, Michael B. Dwinell |
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Format: | Article |
Language: | English |
Published: |
Cambridge University Press
2018-06-01
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Series: | Journal of Clinical and Translational Science |
Online Access: | https://www.cambridge.org/core/product/identifier/S2059866118000791/type/journal_article |
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