PARP9 knockdown confers protection against chemoresistance and immune escape of breast cancer cells by blocking the PI3K/AKT pathway

Introduction This study probes the mechanism of the PARP9/PI3K/AKT/PD-L1 axis in the chemoresistance and immune escape of breast cancer cells. Material and methods The expression of related genes was detected in MCF-7/FUL cells. After MCF-7/FUL cells were treated with sh-PARP9 and/or the PI3K/AKT p...

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Bibliographic Details
Main Authors: Tao Hong, Dingxiang Dong, Jun Li, Lin Wang
Format: Article
Language:English
Published: Termedia Publishing House 2023-03-01
Series:Archives of Medical Science
Subjects:
Online Access:https://www.archivesofmedicalscience.com/PARP9-knockdown-confers-protection-against-chemoresistance-and-immune-escape-of-breast,161444,0,2.html