Circulating immune-complexes of IgG/IgM bound to B2-glycoprotein-I associated with complement consumption and thrombocytopenia in antiphospholipid syndrome

Circulating immune-complexes of IgG/IgM bound to B2-glycoprotein-I associated with complement consumption and thrombocytopenia in antiphospholipid syndrome

BackgroundAntiphospholipid syndrome (APS) is a multisystemic autoimmune disorder characterized by thrombotic events and/or gestational morbidity in patients with antiphospholipid antibodies (aPL). In a previous single center study, APS-related clinical manifestations that were not included in the cl...

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Bibliographic Details
Main Authors: Laura Naranjo, Ljudmila Stojanovich, Aleksandra Djokovic, Laura Andreoli, Angela Tincani, Maria Maślińska, Savino Sciascia, Maria Infantino, Sara Garcinuño, Kinga Kostyra-Grabczak, Mariangela Manfredi, Francesca Regola, Natasa Stanisavljevic, Milomir Milanovic, Jovica Saponjski, Dario Roccatello, Irene Cecchi, Massimo Radin, Maurizio Benucci, Daniel Pleguezuelo, Manuel Serrano, Yehuda Shoenfeld, Antonio Serrano
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-09-01
Series:Frontiers in Immunology
Subjects:
circulating immune-complexes
antiphospholipid syndrome
complement factors
platelets
thrombocytopenia
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.957201/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2022.957201/full

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