Network-Based Approaches for Disease-Gene Association Prediction Using Protein-Protein Interaction Networks

Network-Based Approaches for Disease-Gene Association Prediction Using Protein-Protein Interaction Networks

Genome-wide association studies (GWAS) can be used to infer genome intervals that are involved in genetic diseases. However, investigating a large number of putative mutations for GWAS is resource- and time-intensive. Network-based computational approaches are being used for efficient disease-gene a...

Full description

Bibliographic Details
Main Authors:	Yoonbee Kim, Jong-Hoon Park, Young-Rae Cho
Format:	Article
Language:	English
Published:	MDPI AG 2022-07-01
Series:	International Journal of Molecular Sciences
Subjects:	disease-gene associations disease gene prioritization protein-protein interaction networks disease networks heterogeneous networks
Online Access:	https://www.mdpi.com/1422-0067/23/13/7411

Similar Items

Predicting Drug–Gene–Disease Associations by Tensor Decomposition for Network-Based Computational Drug Repositioning
by: Yoonbee Kim, et al.
Published: (2023-07-01)

Drug-Disease Association Prediction Using Heterogeneous Networks for Computational Drug Repositioning
by: Yoonbee Kim, et al.
Published: (2022-10-01)

Disease–Gene Networks of Skin Pigmentation Disorders and Reconstruction of Protein–Protein Interaction Networks
by: Cian D’Arcy, et al.
Published: (2022-12-01)

Relating Disease-Gene Interaction Network With Disease-Associated ncRNAs
by: Hailin Chen, et al.
Published: (2019-01-01)

A novel candidate disease gene prioritization method using deep graph convolutional networks and semi-supervised learning
by: Saeid Azadifar, et al.
Published: (2022-10-01)

Entropy-Based Graph Clustering of PPI Networks for Predicting Overlapping Functional Modules of Proteins
by: Hoyeon Jeong, et al.
Published: (2021-09-01)

Multi-view heterogeneous molecular network representation learning for protein–protein interaction prediction
by: Xiao-Rui Su, et al.
Published: (2022-06-01)

Ensemble disease gene prediction by clinical sample-based networks
by: Ping Luo, et al.
Published: (2020-03-01)

Prioritizing disease genes with an improved dual label propagation framework
by: Yaogong Zhang, et al.
Published: (2018-02-01)

Mining disease genes using integrated protein–protein interaction and gene–gene co‐regulation information
by: Jin Li, et al.
Published: (2015-01-01)

Network Protein Interaction in Parkinson’s Disease and Periodontitis Interplay: A Preliminary Bioinformatic Analysis
by: João Botelho, et al.
Published: (2020-11-01)

PFP-GO: Integrating protein sequence, domain and protein-protein interaction information for protein function prediction using ranked GO terms
by: Kaustav Sengupta, et al.
Published: (2022-09-01)

Disease-gene prediction based on preserving structure network embedding
by: Jinlong Ma, et al.
Published: (2023-02-01)

Exploring novel disease-disease associations based on multi-view fusion network
by: Xiaoxi Yang, et al.
Published: (2023-01-01)

Network Protein Interaction in the Link between Stroke and Periodontitis Interplay: A Pilot Bioinformatic Analysis
by: Yago Leira, et al.
Published: (2021-05-01)

Graph Neural Network for Protein–Protein Interaction Prediction: A Comparative Study
by: Hang Zhou, et al.
Published: (2022-09-01)

Biological interacting units identified in human protein networks reveal tissue-functional diversification and its impact on disease
by: Marina L. García-Vaquero, et al.
Published: (2022-01-01)

APPINetwork: an R package for building and computational analysis of protein–protein interaction networks
by: Simon Gosset, et al.
Published: (2022-11-01)

Applying Protein–Protein Interactions and Complex Networks to Identify Novel Genes in Retinitis Pigmentosa Pathogenesis
by: Su-Bin Yoon, et al.
Published: (2022-04-01)

Construction and contextualization approaches for protein-protein interaction networks
by: Apurva Badkas, et al.
Published: (2022-01-01)

Construction of the coexpression network involved in the pathogenesis of thyroid eye disease via bioinformatics analysis
by: Jinxing Hu, et al.
Published: (2022-09-01)

ANALYSIS OF THE INTERACTIONS OF NEURONAL APOPTOSIS GENES IN THE ASSOCIATIVE GENE NETWORK OF PARKINSON’S DISEASE
by: M. A. Yankina, et al.
Published: (2018-03-01)

Drug and Protein Interaction Network Construction for Drug Repurposing in Alzheimer’s Disease
by: Georgios N. Dimitrakopoulos, et al.
Published: (2023-10-01)

Construction and analysis of the protein-protein interaction network of visual system in Drosophila
by: JiaNing Sun, et al.
Published: (2023-12-01)

Orthologs of Human-Disease-Associated Genes in Plants Are Involved in Regulating Leaf Senescence
by: Hou-Ling Wang, et al.
Published: (2023-02-01)

Biochemical Pathway and Protein-Network Analysis of Dental Caries Based on Systems Biology Approaches
by: Zeinab Mohamadi, et al.
Published: (2023-06-01)

Integration of Protein-Protein Interaction Networks and Gene Expression Profiles Helps Detect Pancreatic Adenocarcinoma Candidate Genes
by: Lili Su, et al.
Published: (2022-05-01)

Molecular Characterization, Protein–Protein Interaction Network, and Evolution of Four Glutathione Peroxidases from <i>Tetrahymena thermophila</i>
by: Diana Ferro, et al.
Published: (2020-10-01)

A disease-related essential protein prediction model based on the transfer neural network
by: Sisi Chen, et al.
Published: (2023-01-01)

Protein complex prediction in large protein–protein interaction network
by: Md. Shahidul Islam, et al.
Published: (2022-01-01)

Identification of gene biomarkers for brain diseases via multi-network topological semantics extraction and graph convolutional network
by: Ping Zhang, et al.
Published: (2024-02-01)

Comparison of Hubs in Effective Normal and Tumor Protein Interaction Networks
by: Mitra Mirzarezaee, et al.
Published: (2010-11-01)

Comparison of Hubs in Effective Normal and Tumor Protein Interaction Networks
by: Mitra Mirzarezaee, et al.
Published: (2010-11-01)

A predicted protein interactome identifies conserved global networks and disease resistance subnetworks in maize.
by: Matt eGeisler, et al.
Published: (2015-06-01)

Identification of drug and protein-protein interaction network among stress and depression: A bioinformatics approach
by: Md. Abul Basar, et al.
Published: (2023-01-01)

Multivariate Entropy Characterizes the Gene Expression and Protein-Protein Networks in Four Types of Cancer
by: Angel Juarez-Flores, et al.
Published: (2018-02-01)

Bioinformatics analysis of gene expression profile and functional analysis in periodontitis and Parkinson’s disease
by: Xiaofeng Wang, et al.
Published: (2022-11-01)

Biomarker Gene Signature Discovery Integrating Network Knowledge
by: Holger Fröhlich, et al.
Published: (2012-02-01)

Comprehensive characterization of human–virus protein-protein interactions reveals disease comorbidities and potential antiviral drugs
by: Si Li, et al.
Published: (2022-01-01)

Protein–Protein Interaction (PPI) Network of Zebrafish Oestrogen Receptors: A Bioinformatics Workflow
by: Rabiatul-Adawiah Zainal-Abidin, et al.
Published: (2022-04-01)