The impact of fetal gender on prematurity in dichorionic twin gestations after in vitro fertilization

<p>Abstract</p> <p>Background</p> <p>Impact of fetal gender on prematurity has been primarily investigated in singleton pregnancies. In an attempt to understand better how fetal gender may affect gestational length in twin gestations after in vitro fertilization, same-s...

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Main Authors: Barad David H, Worda Christof, Stammler-Safar Maria, Klein Katharina, Weghofer Andrea, Husslein Peter, Gleicher Norbert
Format: Article
Language:English
Published: BMC 2010-06-01
Series:Reproductive Biology and Endocrinology
Online Access:http://www.rbej.com/content/8/1/57
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author Barad David H
Worda Christof
Stammler-Safar Maria
Klein Katharina
Weghofer Andrea
Husslein Peter
Gleicher Norbert
author_facet Barad David H
Worda Christof
Stammler-Safar Maria
Klein Katharina
Weghofer Andrea
Husslein Peter
Gleicher Norbert
author_sort Barad David H
collection DOAJ
description <p>Abstract</p> <p>Background</p> <p>Impact of fetal gender on prematurity has been primarily investigated in singleton pregnancies. In an attempt to understand better how fetal gender may affect gestational length in twin gestations after in vitro fertilization, same-sex twins and opposite twins were compared for pregnancy duration.</p> <p>Methods</p> <p>This study evaluated 113 women at ages 20 to 39 years with consecutive dichorionic-diamniotic twin gestations after assisted reproduction. All pregnancies were results of fresh in vitro fertilization (IVF) cycles with use of autologous oocytes and sperm and were delivered at up to 37 weeks of gestation at a University-based high-risk, maternal-fetal medicine unit.</p> <p>Results</p> <p>Both groups did not differ in baseline characteristics, such as maternal ages, indications for fertility treatments, number of previous IVF attempts, body mass index and parity. Opposite sex- twins, however, presented with significantly shorter gestational age at birth (32.9 +/- 3.4 weeks) than same-sex twins (34.3 +/- 2.5 weeks), (p < 0.05). Younger maternal age was also associated with shorter pregnancy duration (p < 0.05).</p> <p>Conclusions</p> <p>Fetal gender mix serves as risk factor for more significant prematurity in dichorionic-diamniotic twins after assisted reproduction with opposite sex twins at higher risk than same sex-twins.</p>
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spelling doaj.art-a5d0ac42f3e541afa2aaaa2161fd9db32022-12-21T19:13:18ZengBMCReproductive Biology and Endocrinology1477-78272010-06-01815710.1186/1477-7827-8-57The impact of fetal gender on prematurity in dichorionic twin gestations after in vitro fertilizationBarad David HWorda ChristofStammler-Safar MariaKlein KatharinaWeghofer AndreaHusslein PeterGleicher Norbert<p>Abstract</p> <p>Background</p> <p>Impact of fetal gender on prematurity has been primarily investigated in singleton pregnancies. In an attempt to understand better how fetal gender may affect gestational length in twin gestations after in vitro fertilization, same-sex twins and opposite twins were compared for pregnancy duration.</p> <p>Methods</p> <p>This study evaluated 113 women at ages 20 to 39 years with consecutive dichorionic-diamniotic twin gestations after assisted reproduction. All pregnancies were results of fresh in vitro fertilization (IVF) cycles with use of autologous oocytes and sperm and were delivered at up to 37 weeks of gestation at a University-based high-risk, maternal-fetal medicine unit.</p> <p>Results</p> <p>Both groups did not differ in baseline characteristics, such as maternal ages, indications for fertility treatments, number of previous IVF attempts, body mass index and parity. Opposite sex- twins, however, presented with significantly shorter gestational age at birth (32.9 +/- 3.4 weeks) than same-sex twins (34.3 +/- 2.5 weeks), (p < 0.05). Younger maternal age was also associated with shorter pregnancy duration (p < 0.05).</p> <p>Conclusions</p> <p>Fetal gender mix serves as risk factor for more significant prematurity in dichorionic-diamniotic twins after assisted reproduction with opposite sex twins at higher risk than same sex-twins.</p>http://www.rbej.com/content/8/1/57
spellingShingle Barad David H
Worda Christof
Stammler-Safar Maria
Klein Katharina
Weghofer Andrea
Husslein Peter
Gleicher Norbert
The impact of fetal gender on prematurity in dichorionic twin gestations after in vitro fertilization
Reproductive Biology and Endocrinology
title The impact of fetal gender on prematurity in dichorionic twin gestations after in vitro fertilization
title_full The impact of fetal gender on prematurity in dichorionic twin gestations after in vitro fertilization
title_fullStr The impact of fetal gender on prematurity in dichorionic twin gestations after in vitro fertilization
title_full_unstemmed The impact of fetal gender on prematurity in dichorionic twin gestations after in vitro fertilization
title_short The impact of fetal gender on prematurity in dichorionic twin gestations after in vitro fertilization
title_sort impact of fetal gender on prematurity in dichorionic twin gestations after in vitro fertilization
url http://www.rbej.com/content/8/1/57
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