Impact of chronic khat ( Forsk) chewing on pulmonary function test and oxygen saturation in humans: A comparative study
Background: Chronic consumption of khat affects many organ systems and leads to various health disturbances in the chewers. Few studies examined the acute effects of khat ingestion on lung function parameters. However, studies which assessed the long-term effects of khat chewing on pulmonary functio...
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| Format: | Article |
| Language: | English |
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SAGE Publishing
2019-01-01
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| Series: | SAGE Open Medicine |
| Online Access: | https://doi.org/10.1177/2050312118824616 |
| _version_ | 1828483041136214016 |
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| author | Gashaw Garedew Woldeamanuel Teshome Gensa Geta |
| author_facet | Gashaw Garedew Woldeamanuel Teshome Gensa Geta |
| author_sort | Gashaw Garedew Woldeamanuel |
| collection | DOAJ |
| description | Background: Chronic consumption of khat affects many organ systems and leads to various health disturbances in the chewers. Few studies examined the acute effects of khat ingestion on lung function parameters. However, studies which assessed the long-term effects of khat chewing on pulmonary function parameters and oxygen saturation are lacking. Objective: The aim of this study was to assess the impact of chronic Khat chewing on pulmonary function parameters and oxygen saturation among chronic Khat chewers in Wolkite, Ethiopia. Methods: A community-based comparative cross-sectional study was conducted in Wolkite, Ethiopia from 1 June 2018 to 15 August 2018. A total of 324 participants, 162 khat chewers and 162 non-chewers were included in the study. The data were collected through face-to-face interview by trained data collectors. British Medical Research Council respiratory questionnaire was used to assess respiratory symptoms. A spirometer was used to assess various lung function parameters. Moreover, oxygen saturation of hemoglobin was measured using pulse oximeter. Data were entered into CSPro version 6.2 and analyzed using SPSS version 23. Results: This study showed statistically significant (p < 0.05) reduction in the mean values of forced vital capacity, forced expiratory volume in first second and maximum ventilation volume among khat chewers as compared to non-chewers. There was no significant difference in the mean values of other lung function parameters between the two groups. Similarly, there was no significant difference (p = 0.642) in mean oxygen saturation of hemoglobin (SaO 2 ) across the two groups. Conclusion: It is evident from this study that long-term khat consumption is associated with decreased mean forced vital capacity, forced expiratory volume in first second and maximum ventilation volume. Hence, there is a need for further study to strengthen the current findings and to explore the mechanisms of khat chewing effect on lung function parameters. |
| first_indexed | 2024-12-11T08:27:16Z |
| format | Article |
| id | doaj.art-a5d3516089374c3ca857329b6beda88c |
| institution | Directory Open Access Journal |
| issn | 2050-3121 |
| language | English |
| last_indexed | 2024-12-11T08:27:16Z |
| publishDate | 2019-01-01 |
| publisher | SAGE Publishing |
| record_format | Article |
| series | SAGE Open Medicine |
| spelling | doaj.art-a5d3516089374c3ca857329b6beda88c2022-12-22T01:14:31ZengSAGE PublishingSAGE Open Medicine2050-31212019-01-01710.1177/2050312118824616Impact of chronic khat ( Forsk) chewing on pulmonary function test and oxygen saturation in humans: A comparative studyGashaw Garedew WoldeamanuelTeshome Gensa GetaBackground: Chronic consumption of khat affects many organ systems and leads to various health disturbances in the chewers. Few studies examined the acute effects of khat ingestion on lung function parameters. However, studies which assessed the long-term effects of khat chewing on pulmonary function parameters and oxygen saturation are lacking. Objective: The aim of this study was to assess the impact of chronic Khat chewing on pulmonary function parameters and oxygen saturation among chronic Khat chewers in Wolkite, Ethiopia. Methods: A community-based comparative cross-sectional study was conducted in Wolkite, Ethiopia from 1 June 2018 to 15 August 2018. A total of 324 participants, 162 khat chewers and 162 non-chewers were included in the study. The data were collected through face-to-face interview by trained data collectors. British Medical Research Council respiratory questionnaire was used to assess respiratory symptoms. A spirometer was used to assess various lung function parameters. Moreover, oxygen saturation of hemoglobin was measured using pulse oximeter. Data were entered into CSPro version 6.2 and analyzed using SPSS version 23. Results: This study showed statistically significant (p < 0.05) reduction in the mean values of forced vital capacity, forced expiratory volume in first second and maximum ventilation volume among khat chewers as compared to non-chewers. There was no significant difference in the mean values of other lung function parameters between the two groups. Similarly, there was no significant difference (p = 0.642) in mean oxygen saturation of hemoglobin (SaO 2 ) across the two groups. Conclusion: It is evident from this study that long-term khat consumption is associated with decreased mean forced vital capacity, forced expiratory volume in first second and maximum ventilation volume. Hence, there is a need for further study to strengthen the current findings and to explore the mechanisms of khat chewing effect on lung function parameters.https://doi.org/10.1177/2050312118824616 |
| spellingShingle | Gashaw Garedew Woldeamanuel Teshome Gensa Geta Impact of chronic khat ( Forsk) chewing on pulmonary function test and oxygen saturation in humans: A comparative study SAGE Open Medicine |
| title | Impact of chronic khat ( Forsk) chewing on pulmonary function test and oxygen saturation in humans: A comparative study |
| title_full | Impact of chronic khat ( Forsk) chewing on pulmonary function test and oxygen saturation in humans: A comparative study |
| title_fullStr | Impact of chronic khat ( Forsk) chewing on pulmonary function test and oxygen saturation in humans: A comparative study |
| title_full_unstemmed | Impact of chronic khat ( Forsk) chewing on pulmonary function test and oxygen saturation in humans: A comparative study |
| title_short | Impact of chronic khat ( Forsk) chewing on pulmonary function test and oxygen saturation in humans: A comparative study |
| title_sort | impact of chronic khat forsk chewing on pulmonary function test and oxygen saturation in humans a comparative study |
| url | https://doi.org/10.1177/2050312118824616 |
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