A small amount of cyclooxygenase 2 (COX2) is constitutively expressed in platelets

Cyclooxygenase (COX) is the rate-limiting enzyme in conversion of arachidonic acid to prostanoids, and has two isoforms, COX1 and COX2, which share ~65% amino acid homology. COX1 is universally expressed in many cell types including platelets; however, expression of COX2 is known to be more limited....

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Bibliographic Details
Main Authors: Qianghua Hu, Min Soon Cho, Perumal Thiagarajan, Fleur M. Aung, Anil K. Sood, Vahid Afshar-Kharghan
Format: Article
Language:English
Published: Taylor & Francis Group 2017-01-01
Series:Platelets
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Online Access:http://dx.doi.org/10.1080/09537104.2016.1203406