Successful Treatment of Plasmacytosis Circumorificialis with Topical Tacrolimus: Two Case Reports and an Immunohistochemical Study

Successful Treatment of Plasmacytosis Circumorificialis with Topical Tacrolimus: Two Case Reports and an Immunohistochemical Study

Plasmacytosis circumorificialis (PLC), a benign chronic inflammatory disease with an unknown pathogenesis, is characterized by erythema, erosion nodules and ulcers around the openings of the human body. In this report, we describe two cases of PLC successfully treated with topical tacrolimus. Intere...

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Bibliographic Details
Main Authors: Taku Fujimura, Sadanori Furudate, Masaya Ishibashi, Yumi Kambayashi, Gen-ichi Tojo, Chihiro Wakusawa, Hiroshi Mayama, Setsuya Aiba
Format: Article
Language:English
Published: Karger Publishers 2013-03-01
Series:Case Reports in Dermatology
Subjects:
Proinflammatory cytokine
CD163+ macrophages
IL-17
Plasmacytosis circumorificialis
Tacrolimus
Online Access:http://www.karger.com/Article/FullText/350184

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