CEBPD modulates the airway smooth muscle transcriptomic response to glucocorticoids

CEBPD modulates the airway smooth muscle transcriptomic response to glucocorticoids

Abstract Background CCAAT/Enhancer Binding Protein D (CEBPD), a pleiotropic glucocorticoid-responsive transcription factor, modulates inflammatory responses. Of relevance to asthma, expression of CEBPD in airway smooth muscle (ASM) increases with glucocorticoid exposure. We sought to characterize CE...

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Bibliographic Details
Main Authors: Mengyuan Kan, Maoyun Sun, Xiaofeng Jiang, Avantika R. Diwadkar, Vishal Parikh, Gaoyuan Cao, Eric Gebski, William Jester, Bo Lan, Reynold A. Panettieri, Cynthia Koziol-White, Quan Lu, Blanca E. Himes
Format: Article
Language:English
Published: BMC 2022-07-01
Series:Respiratory Research
Subjects:
Airway smooth muscle
Asthma
CEBPD
Inflammatory response
Glucocorticoid response
RNA-Seq
Online Access:https://doi.org/10.1186/s12931-022-02119-1

Internet

https://doi.org/10.1186/s12931-022-02119-1

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