Partial penectomy for severe penile ulceration caused by cholesterol crystal embolization

Introduction Cholesterol crystal embolism is a rare microembolic disease caused by cholesterol crystals that can present with various symptoms after vascular surgery, catheterization, or anticoagulation therapy. We report a case of penile ulceration caused by cholesterol crystal embolism. Case prese...

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Main Authors: Toshiki Matsushima, Kensuke Mitsunari, Nobuhide Maekawa, Shota Yamada, Hidenori Ito, Hiroki Kurata, Yuichiro Nakamura, Tomohiro Matsuo, Kojiro Ohba, Ryoichi Imamura
Format: Article
Language:English
Published: Wiley 2023-11-01
Series:IJU Case Reports
Subjects:
Online Access:https://doi.org/10.1002/iju5.12631
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author Toshiki Matsushima
Kensuke Mitsunari
Nobuhide Maekawa
Shota Yamada
Hidenori Ito
Hiroki Kurata
Yuichiro Nakamura
Tomohiro Matsuo
Kojiro Ohba
Ryoichi Imamura
author_facet Toshiki Matsushima
Kensuke Mitsunari
Nobuhide Maekawa
Shota Yamada
Hidenori Ito
Hiroki Kurata
Yuichiro Nakamura
Tomohiro Matsuo
Kojiro Ohba
Ryoichi Imamura
author_sort Toshiki Matsushima
collection DOAJ
description Introduction Cholesterol crystal embolism is a rare microembolic disease caused by cholesterol crystals that can present with various symptoms after vascular surgery, catheterization, or anticoagulation therapy. We report a case of penile ulceration caused by cholesterol crystal embolism. Case presentation A 72‐year‐old man undergoing maintenance dialysis for end‐stage renal failure presented with penile pain and a black glans ulcer. Despite low‐density lipoprotein apheresis, he was referred to our hospital because of lack of improvement. Based on his medical history and clinical presentation, including artificial vascular replacement and right toe amputation, cholesterol crystal embolism was suspected and partial penectomy was performed, thus confirming the diagnosis. Penile pain resolved after surgery, and he was discharged on Day 10. Unfortunately, he died after small bowel perforation developed 2 months after surgery. Conclusion Penile ulcers caused by cholesterol crystal embolism may indicate the severity and progression of disease and typically require surgical intervention.
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spelling doaj.art-a5ded9f937f047419480f06b09225a352023-11-15T06:01:08ZengWileyIJU Case Reports2577-171X2023-11-016639439710.1002/iju5.12631Partial penectomy for severe penile ulceration caused by cholesterol crystal embolizationToshiki Matsushima0Kensuke Mitsunari1Nobuhide Maekawa2Shota Yamada3Hidenori Ito4Hiroki Kurata5Yuichiro Nakamura6Tomohiro Matsuo7Kojiro Ohba8Ryoichi Imamura9Department of Urology Nagasaki University Graduate School of Biomedical Sciences Nagasaki JapanDepartment of Urology Nagasaki University Graduate School of Biomedical Sciences Nagasaki JapanDepartment of Urology Nagasaki University Graduate School of Biomedical Sciences Nagasaki JapanDepartment of Urology Nagasaki University Graduate School of Biomedical Sciences Nagasaki JapanDepartment of Urology Nagasaki University Graduate School of Biomedical Sciences Nagasaki JapanDepartment of Urology Nagasaki University Graduate School of Biomedical Sciences Nagasaki JapanDepartment of Urology Nagasaki University Graduate School of Biomedical Sciences Nagasaki JapanDepartment of Urology Nagasaki University Graduate School of Biomedical Sciences Nagasaki JapanDepartment of Urology Nagasaki University Graduate School of Biomedical Sciences Nagasaki JapanDepartment of Urology Nagasaki University Graduate School of Biomedical Sciences Nagasaki JapanIntroduction Cholesterol crystal embolism is a rare microembolic disease caused by cholesterol crystals that can present with various symptoms after vascular surgery, catheterization, or anticoagulation therapy. We report a case of penile ulceration caused by cholesterol crystal embolism. Case presentation A 72‐year‐old man undergoing maintenance dialysis for end‐stage renal failure presented with penile pain and a black glans ulcer. Despite low‐density lipoprotein apheresis, he was referred to our hospital because of lack of improvement. Based on his medical history and clinical presentation, including artificial vascular replacement and right toe amputation, cholesterol crystal embolism was suspected and partial penectomy was performed, thus confirming the diagnosis. Penile pain resolved after surgery, and he was discharged on Day 10. Unfortunately, he died after small bowel perforation developed 2 months after surgery. Conclusion Penile ulcers caused by cholesterol crystal embolism may indicate the severity and progression of disease and typically require surgical intervention.https://doi.org/10.1002/iju5.12631cholesterol crystal embolismpartial penectomypenile ulceration
spellingShingle Toshiki Matsushima
Kensuke Mitsunari
Nobuhide Maekawa
Shota Yamada
Hidenori Ito
Hiroki Kurata
Yuichiro Nakamura
Tomohiro Matsuo
Kojiro Ohba
Ryoichi Imamura
Partial penectomy for severe penile ulceration caused by cholesterol crystal embolization
IJU Case Reports
cholesterol crystal embolism
partial penectomy
penile ulceration
title Partial penectomy for severe penile ulceration caused by cholesterol crystal embolization
title_full Partial penectomy for severe penile ulceration caused by cholesterol crystal embolization
title_fullStr Partial penectomy for severe penile ulceration caused by cholesterol crystal embolization
title_full_unstemmed Partial penectomy for severe penile ulceration caused by cholesterol crystal embolization
title_short Partial penectomy for severe penile ulceration caused by cholesterol crystal embolization
title_sort partial penectomy for severe penile ulceration caused by cholesterol crystal embolization
topic cholesterol crystal embolism
partial penectomy
penile ulceration
url https://doi.org/10.1002/iju5.12631
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