Angiotensin-converting enzyme insertion/deletion gene polymorphism is associated with dermatomyositis

Angiotensin-converting enzyme insertion/deletion gene polymorphism is associated with dermatomyositis

Background and objective: The cornerstone of dermatomyositis (DM) pathogenesis involves vascular disturbance that leads to hypoxia, capillary necrosis and muscle perifascicular atrophy. Hence, the hypothesis is that the angiotensin-converting enzyme (ACE) insertion/deletion (I/D) gene polymorphism c...

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Bibliographic Details
Main Authors: Samuel K Shinjo, Miyuki Uno, Sueli M Oba-Shinjo, Suely KN Marie
Format: Article
Language:English
Published: SAGE Publications 2015-09-01
Series:Journal of the Renin-Angiotensin-Aldosterone System
Online Access:https://doi.org/10.1177/1470320314524995

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