Homologous Recombination and Translesion DNA Synthesis Play Critical Roles on Tolerating DNA Damage Caused by Trace Levels of Hexavalent Chromium.
Contamination of potentially carcinogenic hexavalent chromium (Cr(VI)) in the drinking water is a major public health concern worldwide. However, little information is available regarding the biological effects of a nanomoler amount of Cr(VI). Here, we investigated the genotoxic effects of Cr(VI) at...
Main Authors: | Xu Tian, Keyur Patel, John R Ridpath, Youjun Chen, Yi-Hui Zhou, Dayna Neo, Jean Clement, Minoru Takata, Shunichi Takeda, Julian Sale, Fred A Wright, James A Swenberg, Jun Nakamura |
---|---|
Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2016-01-01
|
Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC5132242?pdf=render |
Similar Items
-
Stalling of Eukaryotic Translesion DNA Polymerases at DNA-Protein Cross-Links
by: Anna V. Yudkina, et al.
Published: (2022-01-01) -
Chronic occupational exposure to hexavalent chromium causes DNA damage in electroplating workers
by: Ren Xiao-Bin, et al.
Published: (2011-04-01) -
Regulation of translesion synthesis DNA polymerase eta by monoubiquitination.
by: Bienko, M, et al.
Published: (2010) -
Characterization of human translesion DNA synthesis across a UV-induced DNA lesion
by: Mark Hedglin, et al.
Published: (2016-10-01) -
Recent Advances in Understanding the Structures of Translesion Synthesis DNA Polymerases
by: Justin A. Ling, et al.
Published: (2022-05-01)