<i>Snail-1</i> Overexpression Correlates with Metastatic Phenotype in BRAF<sup>V600E</sup> Positive Papillary Thyroid Carcinoma

<i>Snail-1</i> Overexpression Correlates with Metastatic Phenotype in BRAF<sup>V600E</sup> Positive Papillary Thyroid Carcinoma

The ability of cancer to metastasize is regulated by various signaling pathways, including transforming growth factor β (TGFβ), also implicated in the upregulation of Snail-1 transcription factor in malignant neoplasms. B-type Raf kinase gene (BRAF)<sup>V600E</sup>, the most common drivi...

Full description

Bibliographic Details
Main Authors:	Katarzyna Wieczorek-Szukala, Janusz Kopczynski, Aldona Kowalska, Andrzej Lewinski
Format:	Article
Language:	English
Published:	MDPI AG 2020-08-01
Series:	Journal of Clinical Medicine
Subjects:	PTC thyroid metastasis Snail-1 BRAF<sup>V600E</sup>
Online Access:	https://www.mdpi.com/2077-0383/9/9/2701

Similar Items

BRAF<sup>V600E</sup> status and clinical characteristics in solitary and multiple papillary thyroid carcinoma: experience of 512 cases at a clinical center in China
by: Zheng Xiangqian, et al.
Published: (2012-06-01)

Association of microRNA Expression and BRAF<sup>V600E</sup> Mutation with Recurrence of Thyroid Cancer
by: Daina Pamedytyte, et al.
Published: (2020-04-01)

BRAF<sup>V600E</sup> Positivity-Dependent Effect of Age on Papillary Thyroid Cancer Recurrence Risk
by: Joonseon Park, et al.
Published: (2023-11-01)

BRAF<sup>V600E</sup> Induction in Thyrocytes Triggers Important Changes in the miRNAs Content and the Populations of Extracellular Vesicles Released in Thyroid Tumor Microenvironment
by: Ophélie Delcorte, et al.
Published: (2022-03-01)

Characterization and Clinical Utility of <i>BRAF</i><sup>V600</sup> Mutation Detection Using Cell-Free DNA in Patients with Advanced Melanoma
by: Piotr Rutkowski, et al.
Published: (2021-07-01)

Effects of Copper Chelation on BRAF<sup>V600E</sup> Positive Colon Carcinoma Cells
by: Silvia Baldari, et al.
Published: (2019-05-01)

<sup>V600E</sup>BRAF Inhibition Induces Cytoprotective Autophagy through AMPK in Thyroid Cancer Cells
by: Eva Jiménez-Mora, et al.
Published: (2021-06-01)

Design, Synthesis, and Antiproliferative Activity of New 5-Chloro-indole-2-carboxylate and Pyrrolo[3,4-<i>b</i>]indol-3-one Derivatives as Potent Inhibitors of EGFR<sup>T790M</sup>/BRAF<sup>V600E</sup> Pathways
by: Lamya H. Al-Wahaibi, et al.
Published: (2023-01-01)

<i>BRAF<sup>V600E</sup></i> Mutant Allele Frequency (MAF) Influences Melanoma Clinicopathologic Characteristics
by: Xavier Soria, et al.
Published: (2021-10-01)

Nuclear Localization of BRAF<sup>V600E</sup> Is Associated with HMOX-1 Upregulation and Aggressive Behavior of Melanoma Cells
by: Mourad Zerfaoui, et al.
Published: (2022-01-01)

The <i>BRAF<sup>V600E</sup></i> Mutation Is Not a Risk Factor for More Aggressive Tumor Behavior in Radiogenic and Sporadic Papillary Thyroid Carcinoma at a Young Age
by: Liudmyla Zurnadzhy, et al.
Published: (2021-11-01)

Sesquiterpene Lactone Deoxyelephantopin Isolated from <i>Elephantopus scaber</i> and Its Derivative DETD-35 Suppress BRAF<sup>V600E</sup> Mutant Melanoma Lung Metastasis in Mice
by: Biljana Cvetanova, et al.
Published: (2021-03-01)

Genetic Landscape of Papillary Thyroid Carcinoma and Nuclear Architecture: An Overview Comparing Pediatric and Adult Populations
by: Aline Rangel-Pozzo, et al.
Published: (2020-10-01)

<i>BRAF</i><sup>V600E</sup> <i>vs</i>. TIRADS in predicting papillary thyroid cancers in Bethesda system I, III, and V nodules
by: Ya Wu, et al.
Published: (2019-03-01)

Prospective Analysis of <i>TERT</i> Promoter Mutations in Papillary Thyroid Carcinoma at a Single Institution
by: Yun-Suk Choi, et al.
Published: (2021-05-01)

Quinazolin-4-one/3-cyanopyridin-2-one Hybrids as Dual Inhibitors of EGFR and BRAF<sup>V600E</sup>: Design, Synthesis, and Antiproliferative Activity
by: Lamya H. Al-Wahaibi, et al.
Published: (2023-10-01)

Development of Novel Murine BRAF<sup>V600E</sup>-Driven Papillary Thyroid Cancer Cell Lines for Modeling of Disease Progression and Preclinical Evaluation of Therapeutics
by: Grace Purvis Branigan, et al.
Published: (2023-01-01)

Analysis of Expression of Programmed Cell Death Ligand 1 (PD-L1) and <i>BRAF<sup>V600E</sup></i> Mutation in Thyroid Cancer
by: Mizuki Sekino, et al.
Published: (2023-06-01)

Therapeutic Efficacy of Pharmacological Ascorbate on Braf Inhibitor Resistant Melanoma Cells In Vitro and In Vivo
by: Heike Niessner, et al.
Published: (2022-04-01)

BRAF Inhibitors Induce Feedback Activation of RAS Pathway in Thyroid Cancer Cells
by: Elisa Bonaldi, et al.
Published: (2021-05-01)

Discovery of New Quinoline-Based Diarylamides as Potent B-RAF<sup>V600E</sup>/C-RAF Kinase Inhibitors Endowed with Promising In Vitro Anticancer Activity
by: Hyun Ji Kim, et al.
Published: (2023-02-01)

An <sup>1</sup>H NMR- and MS-Based Study of Metabolites Profiling of Garden Snail <i>Helix aspersa</i> Mucus
by: Nikolay G. Vassilev, et al.
Published: (2020-09-01)

Coexisting Germline <i>CHEK2</i> and Somatic <i>BRAF</i><sup>V600E</sup> Mutations in Papillary Thyroid Cancer and Their Association with Clinicopathological Features and Disease Course
by: Danuta Gąsior-Perczak, et al.
Published: (2019-11-01)

Extended Antitumor Responseof a BRAF V600E Papillary Thyroid Carcinoma to Vemurafenib
by: Siraj M. Ali, et al.
Published: (2014-05-01)

Rethinking the role of oncogenes in papillary thyroid cancer initiation
by: Mario eVitale
Published: (2012-06-01)

BRAF V600E and lymph node metastases in papillary thyroid cancer
by: Pan Chen, et al.
Published: (2020-10-01)

Real-World Outcomes of First-Line FOLFIRI Plus Bevacizumab with Irinotecan Dose Escalation versus FOLFOXIRI Plus Bevacizumab in <i>BRAF<sup>V600E</sup></i>-Mutant Metastatic Colorectal Cancer: The Preliminary Data from a Single-Center Observational Study
by: Hsiang-Lin Tsai, et al.
Published: (2023-12-01)

Določanje mutacije V600E v genu BRAF
by: Petra Škerl, et al.
Published: (2010-12-01)

Dramatic Therapeutic Response to Dabrafenib Plus Trametinib in BRAF V600E Mutated Papillary Craniopharyngiomas: A Case Report and Literature Review
by: Morena Fasano, et al.
Published: (2022-01-01)

Na<sup>+</sup>,K<sup>+</sup>-ATPase with Disrupted Na<sup>+</sup> Binding Sites I and III Binds Na<sup>+</sup> with Increased Affinity at Site II and Undergoes Na<sup>+</sup>-Activated Phosphorylation with ATP
by: Hang N. Nielsen, et al.
Published: (2024-01-01)

Genotoxicity Associated with <sup>131</sup>I and <sup>99m</sup>Tc Exposure in Nuclear Medicine Staff: A Physical and Biological Monitoring Study
by: Justyna Miszczyk, et al.
Published: (2022-05-01)

Risk factors for cervical lymph node metastasis in papillary thyroid microcarcinoma: a study of 1,587 patients
by: Xiangqian Zheng, et al.
Published: (2019-03-01)

Thoughtful Response on “MRI-based Texture Analysis for Preoperative Prediction of BRAF V600E Mutation in Papillary Thyroid Carcinoma” [Letter]
by: Panjaitan NSD, et al.
Published: (2023-01-01)

Relationship between BRAF V600E and clinical features in papillary thyroid carcinoma
by: Changjiao Yan, et al.
Published: (2019-07-01)

Thoughtful Response on “MRI-Based Texture Analysis for Preoperative Prediction of BRAF V600E Mutation in Papillary Thyroid Carcinoma” [Response to Letter]
by: Zheng T, et al.
Published: (2023-02-01)

Glutamate-Evoked Ca<sup>2+</sup> Responses in the Rat Suprachiasmatic Nucleus: Involvement of Na<sup>+</sup>/K<sup>+</sup>-ATPase and Na<sup>+</sup>/Ca<sup>2+</sup>-Exchanger
by: Pi-Cheng Cheng, et al.
Published: (2023-03-01)

Oncogenic BRAF(V600E) Induces Clastogenesis and UVB Hypersensitivity
by: Dennis A. Simpson, et al.
Published: (2015-06-01)

BRAF V600E MUTATIONS IN METASTATIC MELANOMA - CASE REPORT
by: Ivana Inić, et al.
Published: (2014-09-01)

BRAF<sup>V600E</sup> Expression in Thyrocytes Causes Recruitment of Immunosuppressive STABILIN-1 Macrophages
by: Catherine Spourquet, et al.
Published: (2022-09-01)

BRAF non-V600E more frequently co-occurs with IDH1/2 mutations in adult patients with gliomas than in patients harboring BRAF V600E but without a survival advantage
by: Wei Wang, et al.
Published: (2021-05-01)