Report of two cases of adenoid cystic carcinoma of Bartholin's gland and review of literature
Objective: Primary adenoid cystic carcinoma (ACC) of Bartholin's gland is a rare gynecologic malignancy. We report two cases from primary treatment to recurrence and the adjuvant treatment. Case Report: A woman aged 37 years presented with a mass on the right posterior labia minor and underwent...
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| Format: | Article |
| Language: | English |
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Elsevier
2013-03-01
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| Series: | Taiwanese Journal of Obstetrics & Gynecology |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S1028455913000223 |
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| author | Shih-Tien Hsu Ren-Ching Wang Chien-Hsing Lu Yu-Min Ke Yi-Ting Chen Min-Min Chou Esther Shih-Cho Ho |
| author_facet | Shih-Tien Hsu Ren-Ching Wang Chien-Hsing Lu Yu-Min Ke Yi-Ting Chen Min-Min Chou Esther Shih-Cho Ho |
| author_sort | Shih-Tien Hsu |
| collection | DOAJ |
| description | Objective: Primary adenoid cystic carcinoma (ACC) of Bartholin's gland is a rare gynecologic malignancy. We report two cases from primary treatment to recurrence and the adjuvant treatment.
Case Report: A woman aged 37 years presented with a mass on the right posterior labia minor and underwent right radical hemi-vulvectomy and right-side inguino-femoral node dissection. Final pathology showed ACC arising from Bartholin's gland with positive margins. She received adjuvant external beam radiation to the pelvis, right vulva, and groin area. However, distal metastasis occurred 42 months after initial treatment and she eventually died of multiple metastases. Another woman aged 48 years presented with a mass on the right posterior labia with intermittent pain. She underwent right hemi-vulvectomy and right inguino-femoral lymph node dissection only because pathology showed ACC of Bartholin's gland with negative surgical margins. Lung metastasis occurred 59 months after initial treatment. She took tamoxifen only and achieved stable disease status for 4 years.
Conclusion: To date, about 70 cases have been reported. We treated our second patient with antiestrogen therapy for 4 years and achieved good quality of life and stable disease status. However, further study on hormone therapy for ACC of Bartholin's gland is needed. |
| first_indexed | 2024-12-23T14:33:20Z |
| format | Article |
| id | doaj.art-a5f33355938343a68c33a9c72fa2a43f |
| institution | Directory Open Access Journal |
| issn | 1028-4559 |
| language | English |
| last_indexed | 2024-12-23T14:33:20Z |
| publishDate | 2013-03-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Taiwanese Journal of Obstetrics & Gynecology |
| spelling | doaj.art-a5f33355938343a68c33a9c72fa2a43f2022-12-21T17:43:25ZengElsevierTaiwanese Journal of Obstetrics & Gynecology1028-45592013-03-0152111311610.1016/j.tjog.2012.10.005Report of two cases of adenoid cystic carcinoma of Bartholin's gland and review of literatureShih-Tien Hsu0Ren-Ching Wang1Chien-Hsing Lu2Yu-Min Ke3Yi-Ting Chen4Min-Min Chou5Esther Shih-Cho Ho6Department of Obstetrics and Gynecology, Taichung Veterans General Hospital, Taichung, TaiwanDepartment of Pathology and Laboratory Medicine, Taichung Veterans General Hospital, Taichung, TaiwanDepartment of Obstetrics and Gynecology, Taichung Veterans General Hospital, Taichung, TaiwanDepartment of Obstetrics and Gynecology, Taichung Veterans General Hospital, Taichung, TaiwanDepartment of Obstetrics and Gynecology, Taichung Veterans General Hospital, Taichung, TaiwanDepartment of Obstetrics and Gynecology, Taichung Veterans General Hospital, Taichung, TaiwanDepartment of Obstetrics and Gynecology, Taichung Veterans General Hospital, Taichung, TaiwanObjective: Primary adenoid cystic carcinoma (ACC) of Bartholin's gland is a rare gynecologic malignancy. We report two cases from primary treatment to recurrence and the adjuvant treatment. Case Report: A woman aged 37 years presented with a mass on the right posterior labia minor and underwent right radical hemi-vulvectomy and right-side inguino-femoral node dissection. Final pathology showed ACC arising from Bartholin's gland with positive margins. She received adjuvant external beam radiation to the pelvis, right vulva, and groin area. However, distal metastasis occurred 42 months after initial treatment and she eventually died of multiple metastases. Another woman aged 48 years presented with a mass on the right posterior labia with intermittent pain. She underwent right hemi-vulvectomy and right inguino-femoral lymph node dissection only because pathology showed ACC of Bartholin's gland with negative surgical margins. Lung metastasis occurred 59 months after initial treatment. She took tamoxifen only and achieved stable disease status for 4 years. Conclusion: To date, about 70 cases have been reported. We treated our second patient with antiestrogen therapy for 4 years and achieved good quality of life and stable disease status. However, further study on hormone therapy for ACC of Bartholin's gland is needed.http://www.sciencedirect.com/science/article/pii/S1028455913000223adenoid cystic carcinomaBartholin's glandchemotherapyradiationradical vulvectomyrecurrence |
| spellingShingle | Shih-Tien Hsu Ren-Ching Wang Chien-Hsing Lu Yu-Min Ke Yi-Ting Chen Min-Min Chou Esther Shih-Cho Ho Report of two cases of adenoid cystic carcinoma of Bartholin's gland and review of literature Taiwanese Journal of Obstetrics & Gynecology adenoid cystic carcinoma Bartholin's gland chemotherapy radiation radical vulvectomy recurrence |
| title | Report of two cases of adenoid cystic carcinoma of Bartholin's gland and review of literature |
| title_full | Report of two cases of adenoid cystic carcinoma of Bartholin's gland and review of literature |
| title_fullStr | Report of two cases of adenoid cystic carcinoma of Bartholin's gland and review of literature |
| title_full_unstemmed | Report of two cases of adenoid cystic carcinoma of Bartholin's gland and review of literature |
| title_short | Report of two cases of adenoid cystic carcinoma of Bartholin's gland and review of literature |
| title_sort | report of two cases of adenoid cystic carcinoma of bartholin s gland and review of literature |
| topic | adenoid cystic carcinoma Bartholin's gland chemotherapy radiation radical vulvectomy recurrence |
| url | http://www.sciencedirect.com/science/article/pii/S1028455913000223 |
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