Side Effects of COVID-19 Vaccination Among Healthcare Workers in Tehran, Iran
Background: Since the emergence of coronavirus disease 2019 (COVID-19), many people have been vaccinated worldwide. Despite the preventive role of vaccines, their side effects face disease management with challenges. This study aims to investigate the side effects of COVID-19 vaccination among healt...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
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Shaheed Beheshti University of Medical Sciences
2023-09-01
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| Series: | International Journal of Medical Toxicology and Forensic Medicine |
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| Online Access: | https://journals.sbmu.ac.ir/ijmtfm/article/view/40536 |
| _version_ | 1797666664491253760 |
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| author | Davood Yadegarynia Shabnam Tehrani Fahimeh Hadavand Shahnam Arshi Zahra Abtahian Amirreza Keyvanfar Azar Darvishi Afshin Zarghi |
| author_facet | Davood Yadegarynia Shabnam Tehrani Fahimeh Hadavand Shahnam Arshi Zahra Abtahian Amirreza Keyvanfar Azar Darvishi Afshin Zarghi |
| author_sort | Davood Yadegarynia |
| collection | DOAJ |
| description | Background: Since the emergence of coronavirus disease 2019 (COVID-19), many people have been vaccinated worldwide. Despite the preventive role of vaccines, their side effects face disease management with challenges. This study aims to investigate the side effects of COVID-19 vaccination among healthcare workers in Tehran, Iran.
Methods: This cross-sectional study was conducted from April to October 2022 on 377 healthcare workers in Tehran, Iran. Data collection was carried out through an interview by a researcher using a checklist assessing systemic and local side effects of COVID-19 vaccines.
Results: The mean age of participants was 36.03±10.24 years, and 68.2% were female. Participants experienced significantly more local (26.5% vs. 14.3%, P<0.001) and systemic (52.0% vs. 31.8%, P<0.001) side effects after the first dose than after the second dose. After the first dose, AstraZeneca (45.9%) caused significantly more local reactions than Sputnik V (21.7%) and Sinopharm (14.5%). AstraZeneca (83.7%) caused significantly more systemic side effects than Sputnik V (50.7%) and Sinopharm (14.5%). The prevalence of local and systemic side effects after the first dose was significantly different in terms of vaccine types (P<0.001). After the second dose, AstraZeneca (20.4%) caused significantly more local reactions than Sputnik V (12.8%) and Sinopharm (10.5%) (P<0.001). Additionally, AstraZeneca (38.8%) and Sputnik V (37.4%) caused significantly more systemic side effects than Sinopharm (7.9%) (P<0.001).
Conclusion: Most healthcare workers in Tehran experienced flu-like symptoms and local reactions at the injection site after vaccination against COVID-19, mainly after the first dose. They had more side effects after vaccination with AstraZeneca and Sputnik V, compared to Sinopharm. |
| first_indexed | 2024-03-11T20:01:40Z |
| format | Article |
| id | doaj.art-a5f53b96e90140c887d4f9c85a241a89 |
| institution | Directory Open Access Journal |
| issn | 2251-8762 2251-8770 |
| language | English |
| last_indexed | 2024-03-11T20:01:40Z |
| publishDate | 2023-09-01 |
| publisher | Shaheed Beheshti University of Medical Sciences |
| record_format | Article |
| series | International Journal of Medical Toxicology and Forensic Medicine |
| spelling | doaj.art-a5f53b96e90140c887d4f9c85a241a892023-10-04T08:27:18ZengShaheed Beheshti University of Medical SciencesInternational Journal of Medical Toxicology and Forensic Medicine2251-87622251-87702023-09-01133405364053610.32598/ijmtfm.v13i3.4053633251Side Effects of COVID-19 Vaccination Among Healthcare Workers in Tehran, IranDavood Yadegarynia0https://orcid.org/0000-0001-9121-0844Shabnam Tehrani1https://orcid.org/0000-0001-7005-5398Fahimeh Hadavand2https://orcid.org/0000-0002-6565-1344Shahnam Arshi3https://orcid.org/0000-0003-0103-7596Zahra Abtahian4https://orcid.org/0000-0001-7167-8503Amirreza Keyvanfar5https://orcid.org/0000-0003-2278-5390Azar Darvishi6https://orcid.org/0000-0003-0673-5035Afshin Zarghi7https://orcid.org/0000-0002-6470-7895Infectious Diseases and Tropical Medicine Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.Infectious Diseases and Tropical Medicine Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.Infectious Diseases and Tropical Medicine Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.Infectious Diseases and Tropical Medicine Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran, Department of Infectious Disease and Tropical Medicine, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.Infectious Diseases and Tropical Medicine Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.Infectious Diseases and Tropical Medicine Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.Infectious Diseases and Tropical Medicine Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.Department of Pharmaceutical Chemistry, School of Pharmacy, Shahid Beheshti University of Medical Sciences, Tehran, Iran.Background: Since the emergence of coronavirus disease 2019 (COVID-19), many people have been vaccinated worldwide. Despite the preventive role of vaccines, their side effects face disease management with challenges. This study aims to investigate the side effects of COVID-19 vaccination among healthcare workers in Tehran, Iran. Methods: This cross-sectional study was conducted from April to October 2022 on 377 healthcare workers in Tehran, Iran. Data collection was carried out through an interview by a researcher using a checklist assessing systemic and local side effects of COVID-19 vaccines. Results: The mean age of participants was 36.03±10.24 years, and 68.2% were female. Participants experienced significantly more local (26.5% vs. 14.3%, P<0.001) and systemic (52.0% vs. 31.8%, P<0.001) side effects after the first dose than after the second dose. After the first dose, AstraZeneca (45.9%) caused significantly more local reactions than Sputnik V (21.7%) and Sinopharm (14.5%). AstraZeneca (83.7%) caused significantly more systemic side effects than Sputnik V (50.7%) and Sinopharm (14.5%). The prevalence of local and systemic side effects after the first dose was significantly different in terms of vaccine types (P<0.001). After the second dose, AstraZeneca (20.4%) caused significantly more local reactions than Sputnik V (12.8%) and Sinopharm (10.5%) (P<0.001). Additionally, AstraZeneca (38.8%) and Sputnik V (37.4%) caused significantly more systemic side effects than Sinopharm (7.9%) (P<0.001). Conclusion: Most healthcare workers in Tehran experienced flu-like symptoms and local reactions at the injection site after vaccination against COVID-19, mainly after the first dose. They had more side effects after vaccination with AstraZeneca and Sputnik V, compared to Sinopharm.https://journals.sbmu.ac.ir/ijmtfm/article/view/40536adverse effectscovid-19 vaccinesiransafetysars-cov-2 |
| spellingShingle | Davood Yadegarynia Shabnam Tehrani Fahimeh Hadavand Shahnam Arshi Zahra Abtahian Amirreza Keyvanfar Azar Darvishi Afshin Zarghi Side Effects of COVID-19 Vaccination Among Healthcare Workers in Tehran, Iran International Journal of Medical Toxicology and Forensic Medicine adverse effects covid-19 vaccines iran safety sars-cov-2 |
| title | Side Effects of COVID-19 Vaccination Among Healthcare Workers in Tehran, Iran |
| title_full | Side Effects of COVID-19 Vaccination Among Healthcare Workers in Tehran, Iran |
| title_fullStr | Side Effects of COVID-19 Vaccination Among Healthcare Workers in Tehran, Iran |
| title_full_unstemmed | Side Effects of COVID-19 Vaccination Among Healthcare Workers in Tehran, Iran |
| title_short | Side Effects of COVID-19 Vaccination Among Healthcare Workers in Tehran, Iran |
| title_sort | side effects of covid 19 vaccination among healthcare workers in tehran iran |
| topic | adverse effects covid-19 vaccines iran safety sars-cov-2 |
| url | https://journals.sbmu.ac.ir/ijmtfm/article/view/40536 |
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