The prostaglandin D2 receptor 2 pathway in asthma: a key player in airway inflammation

Abstract Asthma is characterised by chronic airway inflammation, airway obstruction and hyper-responsiveness. The inflammatory cascade in asthma comprises a complex interplay of genetic factors, the airway epithelium, and dysregulation of the immune response. Prostaglandin D2 (PGD2) is a lipid media...

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Bibliographic Details
Main Authors: Christian Domingo, Oscar Palomares, David A. Sandham, Veit J. Erpenbeck, Pablo Altman
Format: Article
Language:English
Published: BMC 2018-09-01
Series:Respiratory Research
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12931-018-0893-x