Seroprevalence of viral hepatitis B, C and E in TB patients from the Republic of Moldova
Introduction. For the first time, in the Republic of Moldova, there was established the seroprevalence of viral hepatitis B, C and E markers in patients with tuberculosis depending on gender, age and geographical areas. Material and methods. 200 blood samples were collected from patients with tub...
| Main Authors: | , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Asociatia de Biosiguranta si Biosecuritate
2023-01-01
|
| Series: | One Health & Risk Management |
| Subjects: | |
| Online Access: | https://journal.ohrm.bba.md/index.php/journal-ohrm-bba-md/article/view/367 |
| _version_ | 1828070612486062080 |
|---|---|
| author | Octavian SAJIN Constantin SPINU Maria ISAC Nina IZIUMOV Aliona CHERNIAVSKA Alexandru BUGA Sergiu BRENISTER |
| author_facet | Octavian SAJIN Constantin SPINU Maria ISAC Nina IZIUMOV Aliona CHERNIAVSKA Alexandru BUGA Sergiu BRENISTER |
| author_sort | Octavian SAJIN |
| collection | DOAJ |
| description | Introduction. For the first time, in the Republic of Moldova, there was established the seroprevalence of viral hepatitis B, C and E markers in patients with tuberculosis depending on gender, age and geographical areas.
Material and methods. 200 blood samples were collected from patients with tuberculosis and tested by the immuno-fermentative method for presence of viral hepatitis B, C and E markers.
Results. Following the investigations, it was established that the seroprevalence of the anti-HEV Ig marker in patients with tuberculosis is 12.0±2.3%. The seroprevalence of viral hepatitis B marker HBsAg in patients with tuberculosis was 13.5±2.4%, and that of viral hepatitis C anti-HCV – 9.0±2.0%. The study of investigations results for the presence of nominated markers depending on the geographical areas showed a significant statistically difference in the seroprevalence of the anti-HEV IgG marker in TB patients in the Central area of the country compared to the Southern area(p<0.05).
Conclusions. Patients with tuberculosis have a higher risk of developing viral hepatitis B, C and E, mainly affecting people aged 40-49 and > 60 years, including males. |
| first_indexed | 2024-04-11T00:39:25Z |
| format | Article |
| id | doaj.art-a5fc8e11f53c4f37b9474a69b55a31af |
| institution | Directory Open Access Journal |
| issn | 2587-3458 2587-3466 |
| language | English |
| last_indexed | 2024-04-11T00:39:25Z |
| publishDate | 2023-01-01 |
| publisher | Asociatia de Biosiguranta si Biosecuritate |
| record_format | Article |
| series | One Health & Risk Management |
| spelling | doaj.art-a5fc8e11f53c4f37b9474a69b55a31af2023-01-06T10:09:01ZengAsociatia de Biosiguranta si BiosecuritateOne Health & Risk Management2587-34582587-34662023-01-0141586310.38045/ohrm.2023.1.07367Seroprevalence of viral hepatitis B, C and E in TB patients from the Republic of MoldovaOctavian SAJIN0Constantin SPINU1Maria ISAC2Nina IZIUMOV3Aliona CHERNIAVSKA4Alexandru BUGA5Sergiu BRENISTER6National Agency for Public Health, Chisinau, Republic of MoldovaNational Agency for Public Health, Chisinau, Republic of MoldovaNational Agency for Public Health, Chisinau, Republic of MoldovaNational Agency for Public Health, Chisinau, Republic of MoldovaNational Agency for Public Health, Chisinau, Republic of MoldovaMunicipal Clinical Hospital of Pneumology, Chisinau, Republic of MoldovaNational Agency for Public Health, Chisinau, Republic of MoldovaIntroduction. For the first time, in the Republic of Moldova, there was established the seroprevalence of viral hepatitis B, C and E markers in patients with tuberculosis depending on gender, age and geographical areas. Material and methods. 200 blood samples were collected from patients with tuberculosis and tested by the immuno-fermentative method for presence of viral hepatitis B, C and E markers. Results. Following the investigations, it was established that the seroprevalence of the anti-HEV Ig marker in patients with tuberculosis is 12.0±2.3%. The seroprevalence of viral hepatitis B marker HBsAg in patients with tuberculosis was 13.5±2.4%, and that of viral hepatitis C anti-HCV – 9.0±2.0%. The study of investigations results for the presence of nominated markers depending on the geographical areas showed a significant statistically difference in the seroprevalence of the anti-HEV IgG marker in TB patients in the Central area of the country compared to the Southern area(p<0.05). Conclusions. Patients with tuberculosis have a higher risk of developing viral hepatitis B, C and E, mainly affecting people aged 40-49 and > 60 years, including males.https://journal.ohrm.bba.md/index.php/journal-ohrm-bba-md/article/view/367seroprevalencelaboratory investigationsviral hepatitis b, c and etb patients |
| spellingShingle | Octavian SAJIN Constantin SPINU Maria ISAC Nina IZIUMOV Aliona CHERNIAVSKA Alexandru BUGA Sergiu BRENISTER Seroprevalence of viral hepatitis B, C and E in TB patients from the Republic of Moldova One Health & Risk Management seroprevalence laboratory investigations viral hepatitis b, c and e tb patients |
| title | Seroprevalence of viral hepatitis B, C and E in TB patients from the Republic of Moldova |
| title_full | Seroprevalence of viral hepatitis B, C and E in TB patients from the Republic of Moldova |
| title_fullStr | Seroprevalence of viral hepatitis B, C and E in TB patients from the Republic of Moldova |
| title_full_unstemmed | Seroprevalence of viral hepatitis B, C and E in TB patients from the Republic of Moldova |
| title_short | Seroprevalence of viral hepatitis B, C and E in TB patients from the Republic of Moldova |
| title_sort | seroprevalence of viral hepatitis b c and e in tb patients from the republic of moldova |
| topic | seroprevalence laboratory investigations viral hepatitis b, c and e tb patients |
| url | https://journal.ohrm.bba.md/index.php/journal-ohrm-bba-md/article/view/367 |
| work_keys_str_mv | AT octaviansajin seroprevalenceofviralhepatitisbcandeintbpatientsfromtherepublicofmoldova AT constantinspinu seroprevalenceofviralhepatitisbcandeintbpatientsfromtherepublicofmoldova AT mariaisac seroprevalenceofviralhepatitisbcandeintbpatientsfromtherepublicofmoldova AT ninaiziumov seroprevalenceofviralhepatitisbcandeintbpatientsfromtherepublicofmoldova AT alionacherniavska seroprevalenceofviralhepatitisbcandeintbpatientsfromtherepublicofmoldova AT alexandrubuga seroprevalenceofviralhepatitisbcandeintbpatientsfromtherepublicofmoldova AT sergiubrenister seroprevalenceofviralhepatitisbcandeintbpatientsfromtherepublicofmoldova |