Primary adrenal lymphoma as a cause of adrenal insufficiency, a report of two cases
Primary adrenal lymphoma (PAL) is a rare cause of adrenal insufficiency. More than 90% is of B-cell origin. The condition is bilateral in up to 75% of cases, with adrenal insufficiency in two of three patients. We report two cases of adrenal insufficiency presenting at the age of 70 and 79 years,...
| Main Authors: | , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Bioscientifica
2020-03-01
|
| Series: | Endocrinology, Diabetes & Metabolism Case Reports |
| Online Access: | https://edm.bioscientifica.com/view/journals/edm/2020/1/EDM19-0131.xml |
| _version_ | 1818260710164004864 |
|---|---|
| author | Kaja Grønning Archana Sharma Maria Adele Mastroianni Bo Daniel Karlsson Eystein S Husebye Kristian Løvås Ingrid Nermoen |
| author_facet | Kaja Grønning Archana Sharma Maria Adele Mastroianni Bo Daniel Karlsson Eystein S Husebye Kristian Løvås Ingrid Nermoen |
| author_sort | Kaja Grønning |
| collection | DOAJ |
| description | Primary adrenal lymphoma (PAL) is a rare cause of adrenal insufficiency. More than 90% is of B-cell origin. The condition
is bilateral in up to 75% of cases, with adrenal insufficiency in two of three patients. We report two cases of adrenal
insufficiency presenting at the age of 70 and 79 years, respectively. Both patients had negative 21-hydroxylase antibodies
with bilateral adrenal lesions on CT. Biopsy showed B-cell lymphoma. One of the patients experienced intermittent disease
regression on replacement dosage of glucocorticoids. |
| first_indexed | 2024-12-12T18:35:39Z |
| format | Article |
| id | doaj.art-a601422f66bf4a5f8a15f7c08021a080 |
| institution | Directory Open Access Journal |
| issn | 2052-0573 2052-0573 |
| language | English |
| last_indexed | 2024-12-12T18:35:39Z |
| publishDate | 2020-03-01 |
| publisher | Bioscientifica |
| record_format | Article |
| series | Endocrinology, Diabetes & Metabolism Case Reports |
| spelling | doaj.art-a601422f66bf4a5f8a15f7c08021a0802022-12-22T00:15:47ZengBioscientificaEndocrinology, Diabetes & Metabolism Case Reports2052-05732052-05732020-03-01111510.1530/EDM-19-0131Primary adrenal lymphoma as a cause of adrenal insufficiency, a report of two casesKaja Grønning0Archana Sharma1Maria Adele Mastroianni2Bo Daniel Karlsson3Eystein S Husebye4Kristian Løvås5Ingrid Nermoen6Department of Endocrinology, Akershus University Hospital, Lorenskog, NorwayDepartment of Endocrinology, Akershus University Hospital, Lorenskog, NorwayDepartment of Haematology, Akershus University Hospital, Lorenskog, NorwayDepartment of Radiology, Akershus University Hospital, Lorenskog, NorwayDepartment of Clinical Science and K.G. Jebsen Center of Autoimmune Disorders, University of Bergen, Bergen, Norway; Department of Medicine, Haukeland University Hospital, Bergen, NorwayDepartment of Clinical Science and K.G. Jebsen Center of Autoimmune Disorders, University of Bergen, Bergen, Norway; Department of Medicine, Haukeland University Hospital, Bergen, NorwayDepartment of Endocrinology, Akershus University Hospital, Lorenskog, Norway; Institute of Clinical Medicine, Faculty of Medicine, University of Oslo, Oslo, Norway Primary adrenal lymphoma (PAL) is a rare cause of adrenal insufficiency. More than 90% is of B-cell origin. The condition is bilateral in up to 75% of cases, with adrenal insufficiency in two of three patients. We report two cases of adrenal insufficiency presenting at the age of 70 and 79 years, respectively. Both patients had negative 21-hydroxylase antibodies with bilateral adrenal lesions on CT. Biopsy showed B-cell lymphoma. One of the patients experienced intermittent disease regression on replacement dosage of glucocorticoids.https://edm.bioscientifica.com/view/journals/edm/2020/1/EDM19-0131.xml |
| spellingShingle | Kaja Grønning Archana Sharma Maria Adele Mastroianni Bo Daniel Karlsson Eystein S Husebye Kristian Løvås Ingrid Nermoen Primary adrenal lymphoma as a cause of adrenal insufficiency, a report of two cases Endocrinology, Diabetes & Metabolism Case Reports |
| title | Primary adrenal lymphoma as a cause of adrenal insufficiency, a report of two cases |
| title_full | Primary adrenal lymphoma as a cause of adrenal insufficiency, a report of two cases |
| title_fullStr | Primary adrenal lymphoma as a cause of adrenal insufficiency, a report of two cases |
| title_full_unstemmed | Primary adrenal lymphoma as a cause of adrenal insufficiency, a report of two cases |
| title_short | Primary adrenal lymphoma as a cause of adrenal insufficiency, a report of two cases |
| title_sort | primary adrenal lymphoma as a cause of adrenal insufficiency a report of two cases |
| url | https://edm.bioscientifica.com/view/journals/edm/2020/1/EDM19-0131.xml |
| work_keys_str_mv | AT kajagrønning primaryadrenallymphomaasacauseofadrenalinsufficiencyareportoftwocases AT archanasharma primaryadrenallymphomaasacauseofadrenalinsufficiencyareportoftwocases AT mariaadelemastroianni primaryadrenallymphomaasacauseofadrenalinsufficiencyareportoftwocases AT bodanielkarlsson primaryadrenallymphomaasacauseofadrenalinsufficiencyareportoftwocases AT eysteinshusebye primaryadrenallymphomaasacauseofadrenalinsufficiencyareportoftwocases AT kristianløvas primaryadrenallymphomaasacauseofadrenalinsufficiencyareportoftwocases AT ingridnermoen primaryadrenallymphomaasacauseofadrenalinsufficiencyareportoftwocases |