Pupillary behaviour in relation to wavelength and age
Pupil light reflex can be used as a non-invasive ocular predictor of cephalic autonomic nervous system integrity. Spectral sensitivity of the pupil´s response to light has, for some time, been an interesting issue. It has generally, however, only been investigated with the use of white light and stu...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2014-04-01
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| Series: | Frontiers in Human Neuroscience |
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| Online Access: | http://journal.frontiersin.org/Journal/10.3389/fnhum.2014.00221/full |
| _version_ | 1819082636331581440 |
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| author | Luis-Lucio Lobato Rincón Maria del Carmen eCabanillas-Campos Cristina eBonnin-Arias Eva eChamorro Antonio eMurciano-Cespedosa Celia eSánchez-Ramos Roda |
| author_facet | Luis-Lucio Lobato Rincón Maria del Carmen eCabanillas-Campos Cristina eBonnin-Arias Eva eChamorro Antonio eMurciano-Cespedosa Celia eSánchez-Ramos Roda |
| author_sort | Luis-Lucio Lobato Rincón |
| collection | DOAJ |
| description | Pupil light reflex can be used as a non-invasive ocular predictor of cephalic autonomic nervous system integrity. Spectral sensitivity of the pupil´s response to light has, for some time, been an interesting issue. It has generally, however, only been investigated with the use of white light and studies with monochromatic wavelengths are scarce. This study investigates the effects of wavelength and age within three parameters of the pupil light reflex (amplitude of response, latency, and velocity of constriction) in a large sample of younger and older adults (N=97), in mesopic conditions. Subjects were exposed to a single light stimulus at four different wavelengths: white (5600 ºK), blue (450 nm), green (510 nm) and red (600 nm). Data was analysed appropriately, and, when applicable, using the General Linear Model (GLM), Randomised Complete Block Design (RCBD), Student´s t test and/or ANCOVA. Across all subjects, pupillary response to light had the greatest amplitude and shortest latency in white and green light conditions. In regards to age, older subjects (46-78 years) showed an increased latency in white light and decreased velocity of constriction in green light compared to younger subjects (18-45 years old). This study provides data patterns on parameters of wavelength-dependent pupil reflexes to light in adults and it contributes to the large body of pupillometric research. It is hoped that this study will add to the overall evaluation of cephalic autonomic nervous system integrity. |
| first_indexed | 2024-12-21T20:19:49Z |
| format | Article |
| id | doaj.art-a602ccd2629d40a9a544e893c13d8d80 |
| institution | Directory Open Access Journal |
| issn | 1662-5161 |
| language | English |
| last_indexed | 2024-12-21T20:19:49Z |
| publishDate | 2014-04-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Human Neuroscience |
| spelling | doaj.art-a602ccd2629d40a9a544e893c13d8d802022-12-21T18:51:31ZengFrontiers Media S.A.Frontiers in Human Neuroscience1662-51612014-04-01810.3389/fnhum.2014.0022166497Pupillary behaviour in relation to wavelength and ageLuis-Lucio Lobato Rincón0Maria del Carmen eCabanillas-Campos1Cristina eBonnin-Arias2Eva eChamorro3Antonio eMurciano-Cespedosa4Celia eSánchez-Ramos Roda5University Complutense of MadridUniversity Complutense of MadridUniversity Complutense of MadridUniversity Complutense of MadridUniversity Complutense of MadridUniversity Complutense of MadridPupil light reflex can be used as a non-invasive ocular predictor of cephalic autonomic nervous system integrity. Spectral sensitivity of the pupil´s response to light has, for some time, been an interesting issue. It has generally, however, only been investigated with the use of white light and studies with monochromatic wavelengths are scarce. This study investigates the effects of wavelength and age within three parameters of the pupil light reflex (amplitude of response, latency, and velocity of constriction) in a large sample of younger and older adults (N=97), in mesopic conditions. Subjects were exposed to a single light stimulus at four different wavelengths: white (5600 ºK), blue (450 nm), green (510 nm) and red (600 nm). Data was analysed appropriately, and, when applicable, using the General Linear Model (GLM), Randomised Complete Block Design (RCBD), Student´s t test and/or ANCOVA. Across all subjects, pupillary response to light had the greatest amplitude and shortest latency in white and green light conditions. In regards to age, older subjects (46-78 years) showed an increased latency in white light and decreased velocity of constriction in green light compared to younger subjects (18-45 years old). This study provides data patterns on parameters of wavelength-dependent pupil reflexes to light in adults and it contributes to the large body of pupillometric research. It is hoped that this study will add to the overall evaluation of cephalic autonomic nervous system integrity.http://journal.frontiersin.org/Journal/10.3389/fnhum.2014.00221/fullAgingpupil light reflexPupillometrymesopic conditionswavelengthocular predictor |
| spellingShingle | Luis-Lucio Lobato Rincón Maria del Carmen eCabanillas-Campos Cristina eBonnin-Arias Eva eChamorro Antonio eMurciano-Cespedosa Celia eSánchez-Ramos Roda Pupillary behaviour in relation to wavelength and age Frontiers in Human Neuroscience Aging pupil light reflex Pupillometry mesopic conditions wavelength ocular predictor |
| title | Pupillary behaviour in relation to wavelength and age |
| title_full | Pupillary behaviour in relation to wavelength and age |
| title_fullStr | Pupillary behaviour in relation to wavelength and age |
| title_full_unstemmed | Pupillary behaviour in relation to wavelength and age |
| title_short | Pupillary behaviour in relation to wavelength and age |
| title_sort | pupillary behaviour in relation to wavelength and age |
| topic | Aging pupil light reflex Pupillometry mesopic conditions wavelength ocular predictor |
| url | http://journal.frontiersin.org/Journal/10.3389/fnhum.2014.00221/full |
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