Manganese-induced apoptosis through the ROS-activated JNK/FOXO3a signaling pathway in CTX cells, a model of rat astrocytes
Manganese (Mn) is an essential trace element that maintains many normal physiological functions. However, multi-system disorders would occur once overexposure to Mn, especially neurotoxicity. Despite evidence demonstrating the critical role of ROS-activated JNK/FOXO3a signaling pathway in neuronal s...
Main Authors: | Wan-He Li, Zheng-Ting-Yan Xiang, An-Xin Lu, Su-Su Wang, Chong-Huai Yan |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2023-09-01
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Series: | Ecotoxicology and Environmental Safety |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S0147651323008308 |
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