Cyclophilins and Their Functions in Abiotic Stress and Plant–Microbe Interactions
Plants have developed a variety of mechanisms and regulatory pathways to change their gene expression profiles in response to abiotic stress conditions and plant–microbe interactions. The plant–microbe interaction can be pathogenic or beneficial. Stress conditions, both abiotic and pathogenic, negat...
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| Format: | Article |
| Language: | English |
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MDPI AG
2021-09-01
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| Series: | Biomolecules |
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| Online Access: | https://www.mdpi.com/2218-273X/11/9/1390 |
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| author | Przemysław Olejnik Cezary Jerzy Mądrzak Katarzyna Nuc |
| author_facet | Przemysław Olejnik Cezary Jerzy Mądrzak Katarzyna Nuc |
| author_sort | Przemysław Olejnik |
| collection | DOAJ |
| description | Plants have developed a variety of mechanisms and regulatory pathways to change their gene expression profiles in response to abiotic stress conditions and plant–microbe interactions. The plant–microbe interaction can be pathogenic or beneficial. Stress conditions, both abiotic and pathogenic, negatively affect the growth, development, yield and quality of plants, which is very important for crops. In contrast, the plant–microbe interaction could be growth-promoting. One of the proteins involved in plant response to stress conditions and plant–microbe interactions is cyclophilin. Cyclophilins (CyPs), together with FK506-binding proteins (FKBPs) and parvulins, belong to a big family of proteins with peptidyl-prolyl <i>cis-trans</i> isomerase activity (Enzyme Commission (EC) number 5.2.1.8). Genes coding for proteins with the CyP domain are widely expressed in all organisms examined, including bacteria, fungi, animals, and plants. Their different forms can be found in the cytoplasm, endoplasmic reticulum, nucleus, chloroplast, mitochondrion and in the phloem space. They are involved in numerous processes, such as protein folding, cellular signaling, mRNA processing, protein degradation and apoptosis. In the past few years, many new functions, and molecular mechanisms for cyclophilins have been discovered. In this review, we aim to summarize recent advances in cyclophilin research to improve our understanding of their biological functions in plant defense and symbiotic plant–microbe interactions. |
| first_indexed | 2024-03-10T07:51:31Z |
| format | Article |
| id | doaj.art-a610e196024d4700ac03e45d3ed26390 |
| institution | Directory Open Access Journal |
| issn | 2218-273X |
| language | English |
| last_indexed | 2024-03-10T07:51:31Z |
| publishDate | 2021-09-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Biomolecules |
| spelling | doaj.art-a610e196024d4700ac03e45d3ed263902023-11-22T12:11:58ZengMDPI AGBiomolecules2218-273X2021-09-01119139010.3390/biom11091390Cyclophilins and Their Functions in Abiotic Stress and Plant–Microbe InteractionsPrzemysław Olejnik0Cezary Jerzy Mądrzak1Katarzyna Nuc2Department of Biochemistry and Biotechnology, Poznań University of Life Sciences, Dojazd 11, 60-632 Poznań, PolandDepartment of Biochemistry and Biotechnology, Poznań University of Life Sciences, Dojazd 11, 60-632 Poznań, PolandDepartment of Biochemistry and Biotechnology, Poznań University of Life Sciences, Dojazd 11, 60-632 Poznań, PolandPlants have developed a variety of mechanisms and regulatory pathways to change their gene expression profiles in response to abiotic stress conditions and plant–microbe interactions. The plant–microbe interaction can be pathogenic or beneficial. Stress conditions, both abiotic and pathogenic, negatively affect the growth, development, yield and quality of plants, which is very important for crops. In contrast, the plant–microbe interaction could be growth-promoting. One of the proteins involved in plant response to stress conditions and plant–microbe interactions is cyclophilin. Cyclophilins (CyPs), together with FK506-binding proteins (FKBPs) and parvulins, belong to a big family of proteins with peptidyl-prolyl <i>cis-trans</i> isomerase activity (Enzyme Commission (EC) number 5.2.1.8). Genes coding for proteins with the CyP domain are widely expressed in all organisms examined, including bacteria, fungi, animals, and plants. Their different forms can be found in the cytoplasm, endoplasmic reticulum, nucleus, chloroplast, mitochondrion and in the phloem space. They are involved in numerous processes, such as protein folding, cellular signaling, mRNA processing, protein degradation and apoptosis. In the past few years, many new functions, and molecular mechanisms for cyclophilins have been discovered. In this review, we aim to summarize recent advances in cyclophilin research to improve our understanding of their biological functions in plant defense and symbiotic plant–microbe interactions.https://www.mdpi.com/2218-273X/11/9/1390cyclophilinspeptide bond isomerizationstresspathogenesisplant–microbe interaction |
| spellingShingle | Przemysław Olejnik Cezary Jerzy Mądrzak Katarzyna Nuc Cyclophilins and Their Functions in Abiotic Stress and Plant–Microbe Interactions Biomolecules cyclophilins peptide bond isomerization stress pathogenesis plant–microbe interaction |
| title | Cyclophilins and Their Functions in Abiotic Stress and Plant–Microbe Interactions |
| title_full | Cyclophilins and Their Functions in Abiotic Stress and Plant–Microbe Interactions |
| title_fullStr | Cyclophilins and Their Functions in Abiotic Stress and Plant–Microbe Interactions |
| title_full_unstemmed | Cyclophilins and Their Functions in Abiotic Stress and Plant–Microbe Interactions |
| title_short | Cyclophilins and Their Functions in Abiotic Stress and Plant–Microbe Interactions |
| title_sort | cyclophilins and their functions in abiotic stress and plant microbe interactions |
| topic | cyclophilins peptide bond isomerization stress pathogenesis plant–microbe interaction |
| url | https://www.mdpi.com/2218-273X/11/9/1390 |
| work_keys_str_mv | AT przemysławolejnik cyclophilinsandtheirfunctionsinabioticstressandplantmicrobeinteractions AT cezaryjerzymadrzak cyclophilinsandtheirfunctionsinabioticstressandplantmicrobeinteractions AT katarzynanuc cyclophilinsandtheirfunctionsinabioticstressandplantmicrobeinteractions |