Isoprenoid Derivatives of Lysophosphatidylcholines Enhance Insulin and GLP-1 Secretion through Lipid-Binding GPCRs

Isoprenoid Derivatives of Lysophosphatidylcholines Enhance Insulin and GLP-1 Secretion through Lipid-Binding GPCRs

Insulin plays a significant role in carbohydrate homeostasis as the blood glucose lowering hormone. Glucose-induced insulin secretion (GSIS) is augmented by glucagon-like peptide (GLP-1), a gastrointestinal peptide released in response to ingesting nutriments. The secretion of insulin and GLP-1 is m...

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Bibliographic Details
Main Authors: Anna Drzazga, Daria Kamińska, Anna Gliszczyńska, Edyta Gendaszewska-Darmach
Format: Article
Language:English
Published: MDPI AG 2021-05-01
Series:International Journal of Molecular Sciences
Subjects:
diabetes
insulin
GLP-1
GPR40
GPR55
GPR119
Online Access:https://www.mdpi.com/1422-0067/22/11/5748

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