Interplay between charge distribution and DNA in shaping HP1 paralog phase separation and localization
The heterochromatin protein 1 (HP1) family is a crucial component of heterochromatin with diverse functions in gene regulation, cell cycle control, and cell differentiation. In humans, there are three paralogs, HP1α, HP1β, and HP1γ, which exhibit remarkable similarities in their domain architecture...
Main Authors: | Tien M Phan, Young C Kim, Galia T Debelouchina, Jeetain Mittal |
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Format: | Article |
Language: | English |
Published: |
eLife Sciences Publications Ltd
2024-04-01
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Series: | eLife |
Subjects: | |
Online Access: | https://elifesciences.org/articles/90820 |
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